Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26948699 | 0.81 | ALDH1A1 (0.49) | CYP3A4KMT2ASMN1; SMN2ADORA2BADORA2A | |
| SCHEMBL6049268 | 0.78 | — | — | |
| SCHEMBL4348692 | 0.77 | ADRA1D (0.37) | KMT2ACYP1A2MEN1 | |
| SCHEMBL26034489 | 0.76 | TYMP (0.36) | CYP3A4KMT2ASMN1; SMN2ADORA2AALDH1A1 | |
| SCHEMBL490624 | 0.75 | — | — | |
| SCHEMBL18426909 | 0.74 | — | — | |
| SCHEMBL669512 | 0.74 | — | — | |
| SCHEMBL8377767 | 0.74 | ADRA1D (0.31) | — | |
| SCHEMBL1923337 | 0.74 | CYP1A2 (0.44) | CYP3A4KMT2ASMN1; SMN2ADORA2BADORA2A | |
| SCHEMBL8377755 | 0.74 | TYMP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020160969-A1 | Nucleosides and oligonucleotides containing boron clusters | DEPARTMENT OF VETERANS AFFAIRS | 2002-10-31 | — | — | US | claimed |
| EP-1113020-A2 | Nucleosides and oligonucleotides containing boron clusters | EMORY UNIVERSITY (US) | 2001-07-04 | — | — | EP | claimed |
| US-6180766-B1 | OLIGONUCLEOTIDE WITH UNCHARGED INTERNUCLEOTIDE LINKAGE(S) OF 3',5'-O,O-((CARBORAN-1-YL-METHYL)PHOSPHONATE); MADE BY REACTING O-METHYL(O-CARBORAN-1-YL)METHYL PHOSPHONATE WITH PROTECTED NUCLEOSIDE; USE IN BORON NEUTRON CAPTURE THERAPY | DEPARTMENT OF VETERANS AFFAIRS | 2001-01-30 | — | — | US | claimed |
| EP-0788364-A4 | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | UNIV EMORY (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0788364-A1 | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | EMORY UNIVERSITY (US) | 1997-08-13 | — | — | EP | claimed |
| EP-0731808-A4 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | UNIV EMORY (US) | 1997-04-02 | — | — | EP | claimed |
| US-5599796-A | USING BORON CLUSTER-CONTAINING NUCLEOSIDES OR OLIGONUCLEOTIDES; PARTICULARLY EFFECTIVE FOR BLADDER, PROSTATE AND KIDNEY | EMORY UNIVERSITY (US) | 1997-02-04 | — | — | US | claimed |
| EP-0731808-A1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | EMORY UNIVERSITY (US) | 1996-09-18 | — | — | EP | claimed |
| WO-1996014073-A1 | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | EMORY UNIVERSITY (US) | 1996-05-17 | — | — | WO | claimed |
| WO-1995015333-A1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | EMORY UNIVERSITY (US) | 1995-06-08 | — | — | WO | claimed |
| US-20230399423-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2023-12-14 | — | — | US | disclosed |
| US-20230399423-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2023-12-14 | — | — | US | disclosed |
| CN-107001697-B | Novel coupled uracil compounds for vinyl chloride polymer resins | 路博润先进材料公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-107001697-A | Novel Coupled Uracil Compounds for Vinyl Chloride Polymer Resins | 路博润先进材料公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-103068834-B | Phosphoramidites for reverse RNA synthesis | 坎姆根公司 | 2016-10-26 | — | — | CN | disclosed |
| EP-0731808-A1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | EMORY UNIVERSITY (US) | 1996-09-18 | — | — | EP | disclosed |
| WO-1996014073-A1 | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | EMORY UNIVERSITY (US) | 1996-05-17 | — | — | WO | disclosed |
| EP-0402272-B1 | Cell-culturing substrate, cell-culturing substrate unit bioreactor and extracorporeal circulation type therapeutic apparatus | TERUMO CORP (JP) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995015333-A1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | EMORY UNIVERSITY (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0402272-A2 | Cell-culturing substrate, cell-culturing substrate unit bioreactor and extracorporeal circulation type therapeutic apparatus | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160969-A1 | Nucleosides and oligonucleotides containing boron clusters | NUDT1, NTPCR, NAMPT | CYP3A4 4750/4885KMT2A 3357/4885SMN1; SMN2 604/4885 |
| US-20230399423-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | CUTA, PRKDC, PIK3C3 | CYP3A4 1547/4885KMT2A 388/4885SMN1; SMN2 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.