Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL9063842 | 1.00 | CES2 (0.50) | CES2CES1LMNAMEN1KMT2A | |
| SCHEMBL15544421 | 0.83 | CA1 (0.59) | GPR84PPARDFFAR1FFAR4 | |
| SCHEMBL25834839 | 0.83 | CA2 (0.55) | MAPK1GPR84PPARDFFAR1 | |
| SCHEMBL12044763 | 0.83 | CA2 (0.55) | MAPK1GPR84PPARDFFAR1 | |
| SCHEMBL19115177 | 0.83 | CA2 (0.55) | MAPK1GPR84PPARDFFAR1 | |
| SCHEMBL12044409 | 0.83 | CA2 (0.55) | MAPK1GPR84PPARDFFAR1 | |
| Octane SCHEMBL28234048 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD | |
| Pentadecane SCHEMBL28168073 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD | |
| Heptane SCHEMBL28164569 | 0.82 | GPR84 (0.58) | MEN1KMT2AGPR84PPARGPPARD | |
| SCHEMBL19115528 | 0.81 | CA2 (0.59) | MAPK1GPR84PPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194827-A1 | Crystalline forms of Donepezil base | CHEMAGIS LTD. (IL) | 2008-08-14 | — | — | US | disclosed |
| EP-1935884-A2 | New crystalline forms of donepezil base | CHEMAGIS LTD. (IL) | 2008-06-25 | — | — | EP | disclosed |
| EP-1669349-A1 | New crystalline forms of donepezil base | CHEMAGIS LTD. (IL) | 2006-06-14 | — | — | EP | disclosed |
| US-20060122226-A1 | Crystalline forms of Donepezil base | CHEMAGIS LTD. (IL) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194827-A1 | Crystalline forms of Donepezil base | NOTUM, BCHE, ACHE | CES2 1065/4885CES1 1448/4885LMNA 3630/4885 |
| US-20060122226-A1 | Crystalline forms of Donepezil base | NOTUM, BCHE, ACHE | CES2 1065/4885CES1 1448/4885LMNA 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.