Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906758 | 0.85 | CTSS (0.53) | CTSKCTSSNAMPTPKMKMT2A | |
| SCHEMBL14260245 | 0.80 | CTSK (0.78) | CTSKCTSSCTSLNAMPTPKM | |
| SCHEMBL6647675 | 0.79 | KMT2A (0.49) | CTSKNAMPTPKMKMT2AGAA | |
| SCHEMBL4904948 | 0.78 | CTSS (0.62) | CTSKCTSSNAMPTPKMKMT2A | |
| SCHEMBL4904956 | 0.78 | CTSS (0.62) | CTSKCTSSNAMPTPKMKMT2A | |
| SCHEMBL14260244 | 0.73 | CTSK (1.00) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4899274 | 0.68 | CTSK (0.86) | CTSKCTSSCTSLNAMPTCTSB | |
| SCHEMBL4908452 | 0.68 | CTSS (0.70) | CTSKCTSSCTSLNAMPTGAA | |
| SCHEMBL4908456 | 0.68 | CTSS (0.70) | CTSKCTSSCTSLNAMPTGAA | |
| SCHEMBL6405771 | 0.65 | PKM (0.51) | CTSKNAMPTPKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CATALANO JOHN G | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058333-A1 | CYCLOALKYL KETOAMIDES DERIVATIVES USEFUL AS CATHEPSIN K INHIBITORS | CTSK, CTSS, CTSE | CTSK 1/4885CTSS 2/4885CTSL 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.