SCHEMBL4906876

SCHEMBL4906876

O=C(O)c1cc(Cc2ccccc2)c(O)c(Cc2ccccc2)c1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.60
PTPN2 P17706 2/20 0.60
PTPN6 P29350 2/20 0.60
HNF4A P41235 1/20 0.51
BCL2 P10415 2/20 0.50
LDHA P00338 3/20 0.48
LDHB P07195 3/20 0.48
ME2 P23368 1/20 0.48
ME1 P48163 1/20 0.48
ME3 Q16798 1/20 0.48
HMGB1 P09429 1/20 0.47
CXCL12 P48061 1/20 0.47
ACMSD Q8TDX5 1/20 0.46
BCL2L1 Q07817 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28707306 0.80 PTPN1 (0.73) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL1888529 0.79 PTPN1 (0.49) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL9748865 0.78 PTPN1 (0.64) PTPN1PTPN2PTPN6BCL2HMGB1
SCHEMBL3822401 0.77 LDHA (0.49) PTPN1PTPN2PTPN6HNF4ALDHA
SCHEMBL6441850 0.77 PTPN1 (0.62) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL8647439 0.77 PTPN1 (0.48) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL29921822 0.76 HNF4A (0.51) PTPN1PTPN2PTPN6HNF4AACMSD
SCHEMBL10724258 0.76 PTPN1 (0.67) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL10727257 0.76 PTPN1 (0.67) PTPN1PTPN2PTPN6HNF4ABCL2
SCHEMBL11208758 0.76 PTPN1 (0.57) PTPN1PTPN2PTPN6HNF4ABCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0132717-B1 HEAT-SENSITIVE RECORD MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-04-22 EP claimed
US-20080194403-A1 Laser Recording Thermally Sensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-08-14 US disclosed
EP-1707399-B1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-11-28 EP disclosed
US-7232791-B2 Two or more kinds of colorless or pale colored dye precursors (e.g., phthalein dye) are contained in complex fine particles of a polymer of a multivalence isocyanate compound and furthers contain 4,4'-diisocyanate-3,3'-dimethyl-1,1'-biphenyl and/or polymethylenepolyphenylene polyisocyanate. NIPPON PAPER INDUSTRIES, CO., LTD. (JP) 2007-06-19 US disclosed
US-20070099798-A1 Laser recording thermally sensitive recording medium NAGAI TOMOAKI 2007-05-03 US disclosed
EP-1488933-B1 MULTICOLOR THERMAL RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2007-02-28 EP disclosed
EP-1398169-B1 LASER RECORDING TYPE HEAT SENSITIVE RECORDING ELEMENT JUJO PAPER CO LTD (JP) 2006-11-15 EP disclosed
EP-1707399-A1 LASER RECORDING TYPE HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2006-10-04 EP disclosed
US-20060072429-A1 Multicolored thermally recording medium NIPPON PAPER INDUSRIES CO., LTD. (JP) 2006-04-06 US disclosed
EP-1488933-A1 MULTICOLOR THERMAL RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-22 EP disclosed
EP-0778157-B1 A thermal recording medium JUJO PAPER CO LTD (JP) 2001-04-04 EP disclosed
EP-1060904-A2 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-12-20 EP disclosed
EP-1053888-A1 A thermally sensitive recording paper NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-11-22 EP disclosed
EP-0997316-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-03 EP disclosed
US-5811368-A BASIC LEUCO DYE, PHENOLIC COLOR DEVELOPER; IMPROVED STABILITY TO PLASTICIZERS NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-22 US disclosed
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
EP-0778157-A2 A thermal recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-06-11 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed