Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.60 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | CLK2 | P49760 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242729 | 0.84 | AURKA (0.58) | PIP4K2CLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL4909670 | 0.80 | MKNK2 (0.71) | CSNK2A1CSNK2A2CSNK2BGAAAURKB | |
| SCHEMBL4908388 | 0.79 | PIP4K2C (0.61) | PIP4K2CCSNK2A1CSNK2A2CSNK2BLMNA | |
| SCHEMBL26786625 | 0.78 | AURKB (0.63) | AURKBEGFRMAP4K4PIM1CLK4 | |
| Hydrochloric Acid SCHEMBL810092 | 0.78 | PIP4K2C (0.60) | PIP4K2CCSNK2A1CSNK2A2CSNK2BLMNA | |
| SCHEMBL6639881 | 0.75 | LMNA (0.48) | CSNK2A1CSNK2A2CSNK2BLMNATHRB | |
| SCHEMBL5455292 | 0.74 | LMNA (0.73) | PIP4K2CCSNK2A1LMNAMEN1ALDH1A1 | |
| SCHEMBL13861829 | 0.73 | KDR (0.79) | CSNK2A1CSNK2A2CSNK2BLMNATHRB | |
| SCHEMBL3799687 | 0.72 | PIP4K2C (0.52) | PIP4K2CCSNK2A1CSNK2A2CSNK2BLMNA | |
| Hydrochloric Acid SCHEMBL8810503 | 0.71 | AURKB (0.66) | KMT2APOLBGAAAURKBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | MAP4K2, MAP3K6, MAP3K2 | PIP4K2C 333/4885CSNK2A1 390/4885CSNK2A2 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.