Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783485 | 0.91 | NR1H2 (0.54) | NR1H2ALOX15TSHRHSD17B10ADRB1 | |
| SCHEMBL4783093 | 0.84 | PSEN1 (0.43) | NR1H2ALOX15TSHRHSD17B10ADRB1 | |
| SCHEMBL4782325 | 0.84 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL10391218 | 0.83 | APOB (0.52) | NR1H2ALOX15TSHRHSD17B10ADRB1 | |
| SCHEMBL4782323 | 0.82 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL4783187 | 0.80 | NR1H2 (0.44) | NR1H2ALOX15TSHRHSD17B10ADRB1 | |
| SCHEMBL4781822 | 0.80 | NR1H2 (0.42) | NR1H2ALOX15TSHRHSD17B10ADRB1 | |
| SCHEMBL4637035 | 0.79 | SFRP1 (0.62) | — | |
| SCHEMBL10390072 | 0.79 | PTPN7 (0.53) | NR1H2ALOX15TSHRHSD17B10NR1H3 | |
| SCHEMBL10391196 | 0.78 | POLB (0.54) | NR1H2ALOX15TSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061006-A1 | SUBSTITUTED INDAN-2-YL, TETRAHYDRONAPHTHALEN-2-YL, OR DIHYDR0-2H-CHR0MEN-3-YL ARYLSULFONAMIDES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |