Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CPS1 | P31327 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908582 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NPSR1HPGDRAB9AKDM4E | |
| SCHEMBL4898755 | 0.86 | L3MBTL1 (0.42) | ALDH1A1NPSR1HPGDKDM4EL3MBTL1 | |
| SCHEMBL4886246 | 0.85 | KDM4E (0.44) | ALDH1A1NPSR1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4887425 | 0.85 | L3MBTL1 (0.42) | ALDH1A1NPSR1HPGDKDM4EL3MBTL1 | |
| SCHEMBL4883870 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL4895640 | 0.84 | KDM4E (0.53) | ALDH1A1RAB9AKDM4E | |
| SCHEMBL4893189 | 0.83 | L3MBTL1 (0.41) | ALDH1A1NPSR1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4886340 | 0.83 | TSHR (0.51) | ALDH1A1NPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4889473 | 0.82 | L3MBTL1 (0.52) | ALDH1A1NPSR1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL4889525 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1NPSR1HPGDRAB9ACPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885NPSR1 2465/4885HPGD 1356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.