Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | FUT4 | P22083 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31103530 | 0.85 | PTGS2 (0.53) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL298241 | 0.83 | AKR1C3 (0.53) | PTGS2LMNAMAPTHPGDCYP2C9 | |
| SCHEMBL1741372 | 0.80 | PTGS2 (0.44) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9221016 | 0.80 | AKR1C3 (0.46) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL291001 | 0.79 | PTGS2 (0.47) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL15506106 | 0.79 | PTGS2 (0.47) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL15506197 | 0.79 | PTGS2 (0.47) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5850729 | 0.78 | CA1 (0.52) | PTGS2LMNAALDH1A1CA1CA2 | |
| SCHEMBL5964865 | 0.78 | TTR (0.48) | PTGS2LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL32660739 | 0.78 | TDP1 (0.55) | PTGS2LMNAMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976219-B2 | Photo-cleavable primer compositions and methods of use | ORMCO CORPORATION (US) | 2024-05-07 | — | — | US | disclosed |
| US-11739223-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230112086-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2023-04-13 | — | — | US | disclosed |
| US-20230103027-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2023-03-30 | — | — | US | disclosed |
| US-11453790-B2 | Photo-cleavable primer compositions and methods of use | ENVISTA (US) | 2022-09-27 | — | — | US | disclosed |
| US-11352512-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200347248-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-10696698-B2 | Surface primer compositions and methods of use | ORMCO CORPORATION | 2020-06-30 | — | — | US | disclosed |
| US-10689407-B2 | Photo-cleavable primer compositions and methods of use | ENVISTA (US) | 2020-06-23 | — | — | US | disclosed |
| US-8268293-B2 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | MERCK PATENT GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| CN-101163659-B | Antioxidants | MERCK PATENT GMBH | 2012-09-05 | — | — | CN | disclosed |
| US-8106233-B2 | Applying di-2-ethylhexyl 4-hydroxy-3,5-dimethoxy-benzylmalonate; protective action against UV rays, oxidative stress on body cells, counters skin ageing | MERCK PATENT GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080171004-A1 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080152603-A1 | Antioxidants | SUSONITY Commercial GmbH (DE) | 2008-06-26 | — | — | US | disclosed |
| CN-101163659-A | Antioxidants | MERCK PATENT GMBH (DE) | 2008-04-16 | — | — | CN | disclosed |
| EP-1871339-A1 | UV PROTECTION | Merck Patent GmbH (DE) | 2008-01-02 | — | — | EP | disclosed |
| EP-1871735-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111234-A1 | UV PROTECTION | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006111233-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696698-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | AKR1B1 1087/4885PTGS2 3077/4885LMNA 2155/4885 |
| US-20080152603-A1 | Antioxidants | GPX4, GPX1, CAT | AKR1B1 244/4885PTGS2 320/4885LMNA 1949/4885 |
| US-11453790-B2 | Photo-cleavable primer compositions and methods of use | SP1, GPER1, ESR1 | AKR1B1 964/4885PTGS2 2105/4885LMNA 935/4885 |
| US-11352512-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | AKR1B1 1087/4885PTGS2 3077/4885LMNA 2155/4885 |
| US-20080171004-A1 | Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives | HPD, HAAO, UGT1A6 | AKR1B1 1345/4885PTGS2 1873/4885LMNA 565/4885 |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | AKR1B1 1087/4885PTGS2 3077/4885LMNA 2155/4885 |
| US-20200347248-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | AKR1B1 964/4885PTGS2 2105/4885LMNA 935/4885 |
| US-20230112086-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | AKR1B1 964/4885PTGS2 2105/4885LMNA 935/4885 |
| US-11739223-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | AKR1B1 1087/4885PTGS2 3077/4885LMNA 2155/4885 |
| US-10689407-B2 | Photo-cleavable primer compositions and methods of use | SP1, GPER1, ESR1 | AKR1B1 964/4885PTGS2 2105/4885LMNA 935/4885 |
| US-11976219-B2 | Photo-cleavable primer compositions and methods of use | SP1, GPER1, ESR1 | AKR1B1 964/4885PTGS2 2105/4885LMNA 935/4885 |
| US-20230103027-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | AKR1B1 1087/4885PTGS2 3077/4885LMNA 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.