SCHEMBL490903

SCHEMBL490903

C=CCc1nc(N(C)C)c2[nH]cnc2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 5/20 0.47
PDPK1 O15530 2/20 0.47
CHEK1 O14757 1/20 0.47
AURKA O14965 1/20 0.47
CHEK2 O96017 1/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
PRKACA P17612 1/20 0.47
CCNE1 P24864 1/20 0.47
MARK3 P27448 1/20 0.47
RPS6KA3 P51812 1/20 0.47
PRKCD Q05655 1/20 0.47
LRRK2 Q5S007 1/20 0.47
MARK2 Q7KZI7 1/20 0.47
CDK1 P06493 4/20 0.40
CCNB1 P14635 4/20 0.40
CCNA2 P20248 4/20 0.40
CCNA1 P78396 4/20 0.40
MGMT P16455 2/20 0.40
HSD17B10 Q99714 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6533720 0.77 DPP4 (0.51) CDK2PDPK1CDK1CCNB1CCNA2
SCHEMBL5576430 0.77 CDK2 (0.42) CDK2PDPK1CDK1CCNB1CCNA2
SCHEMBL29559859 0.77 PDPK1 (0.54) CDK2PDPK1LRRK2CDK1CCNB1
SCHEMBL325149 0.77 PDPK1 (0.54) CDK2PDPK1LRRK2CDK1CCNB1
SCHEMBL6747380 0.71 CHEK1 (0.56) CDK2PDPK1CHEK1AURKACHEK2
SCHEMBL9705707 0.71 CDK2 (0.56) CDK2PDPK1CHEK1AURKACHEK2
SCHEMBL401117 0.71 PDPK1 (0.59) CDK2PDPK1CHEK1AURKACHEK2
SCHEMBL7359078 0.69 HRH4 (0.43) PDPK1CHEK1HTTMAP3K5LMNA
SCHEMBL4523841 0.68 CDK2 (0.51) CDK2PDPK1CHEK1AURKACHEK2
SCHEMBL1079075 0.67 ALDH1A1 (0.49) CDK2CDK1CCNB1CCNA2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013016198-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR MICROPROPAGATION OF PLANTS BOOSHOOT LLC (US) 2013-01-31 WO claimed
EP-2150100-B1 Method for micropropagation of monocots based on sustained totipotent cell cultures UNIV SOUTH CAROLINA (US) 2012-07-11 EP claimed
US-7863046-B2 Method for micropropagation of monocots based on sustained totipotent cell cultures THE UNIVERSITY OF SOUTH CAROLINA (US) 2011-01-04 US claimed
EP-2150100-A1 METHOD FOR MICROPROPAGATION OF MONOCOTS BASED ON SUSTAINED TOTIPOTENT CELL CULTURES University of South Carolina (US) 2010-02-10 EP claimed
US-20090293157-A1 PRODUCTION OF PROGENITOR CEREAL CELLS CSIR (ZA) 2009-11-26 US claimed
WO-2009093200-A2 PRODUCTION OF PROGENITOR CEREAL CELLS CSIR (ZA) 2009-07-30 WO claimed
WO-2008136797-A1 METHOD FOR MICROPROPAGATION OF MONOCOTS BASED ON SUSTAINED TOTIPOTENT CELL CULTURES UNIVERSITY OF SOUTH CAROLINA (US) 2008-11-13 WO claimed
US-20080282424-A1 Method for micropropagation of monocots based on sustained totipotent cell cultures UNIVERSITY OF SOUTH CAROLINA 2008-11-13 US claimed
US-7303916-B2 Sustained totipotent culture of selected monocot genera UNIVERSITY OF SOUTH CAROLINA (US) 2007-12-04 US claimed
US-20050102719-A1 Sustained totipotent culture of selected monocot genera UNIVERSITY OF SOUTH CAROLINA (US) 2005-05-12 US claimed
US-6821782-B2 SELECTING AN EXPLANT OF LIVING TISSUE FROM THE PLANT AND CULTIVATING THE TISSUE ON A PRIMARY MEDIUM TO PRODUCE TOTIPOTENT TISSUE UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION 2004-11-23 US claimed
US-20020174455-A1 Sustained totipotent culture of selected monocot genera UNIVERSITY OF SOUTH CAROLINA 2002-11-21 US claimed
WO-2002063024-A2 SUSTAINED TOTIPOTENT CULTURE OF SELECTED MONOCOT GENERA THE UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION (US) 2002-08-15 WO claimed
JP-4341192-A None JP disclosed
EP-4017251-A1 IN-VITRO PHOTOAUTOTROPHIC PROPAGATION OF CANNABIS Node Labs, Inc. (US) 2022-06-29 EP disclosed
US-20220174902-A1 In-Vitro Photoautotrophic Propagation of Cannabis NODE LABS, INC. 2022-06-09 US disclosed
WO-1996020010-A1 COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC ORIDIGM CORPORATION (US) 1996-07-04 WO disclosed
JP-H04341192-A PREPARATION OF PILOCARPINE FROM IN VITRO CULTURE OF PILOCARPUS MERCK PATENT GMBH 1992-11-27 JP disclosed
EP-0225916-A1 TRANSFER OF MALE STERILITY IN CARROTS THE UPJOHN COMPANY (US) 1987-06-24 EP disclosed
WO-1986007379-A1 TRANSFER OF MALE STERILITY IN CARROTS THE UPJOHN COMPANY (US) 1986-12-18 WO disclosed