Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34346 | 0.82 | CYP3A4 (0.65) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL3248171 | 0.79 | CYP3A4 (0.61) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL11172315 | 0.77 | CYP3A4 (0.58) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL112595 | 0.77 | — | — | |
| SCHEMBL3238178 | 0.77 | CYP3A4 (0.58) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL8738051 | 0.76 | ACHE (0.68) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL3891211 | 0.74 | ACHE (0.47) | TSHRALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9144824 | 0.74 | CYP3A4 (0.55) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL3326593 | 0.74 | ALDH1A1 (0.65) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL4372246 | 0.74 | CYP3A4 (0.55) | CYP3A4MAPK1TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203790-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-08-08 | — | — | US | claimed |
| WO-2013006971-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-01-17 | — | — | WO | claimed |
| US-9949480-B2 | N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2018-04-24 | — | — | US | disclosed |
| US-9949480-B2 | N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150327547-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150327547-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-11-19 | — | — | US | disclosed |
| US-9096635-B2 | N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096635-B2 | N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096635-B2 | N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140235565-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235565-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-21 | — | — | US | disclosed |
| US-8722937-B2 | Asymmetric disulfides and aryl-alkyl disulfides as anti-bacterial agents | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130203790-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-08-08 | — | — | US | disclosed |
| US-20130203790-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-08-08 | — | — | US | disclosed |
| WO-2013006971-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013006971-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | 221076 ONTARIO INC. (CA) | 2013-01-17 | — | — | WO | disclosed |
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | UNIVERSITY OF SOUTH FLORIDA | 2008-07-31 | — | — | US | disclosed |
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | UNIVERSITY OF SOUTH FLORIDA | 2008-07-31 | — | — | US | disclosed |
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | UNIVERSITY OF SOUTH FLORIDA | 2008-07-31 | — | — | US | disclosed |
| WO-2008059130-A1 | THIONUCLEOSIDES AND PHARMACEUTICAL APPLICATIONS | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182815-A1 | Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) | SQOR, TST, COASY | CYP3A4 2055/4885MAPK1 2416/4885TSHR 4113/4885 |
| US-20130203790-A1 | SULFUR-CONTAINING COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS | MKI67, TST, PCNA | CYP3A4 4681/4885MAPK1 2268/4885TSHR 3453/4885 |
| US-20150327547-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | COASY, SQOR, TST | CYP3A4 1922/4885MAPK1 3752/4885TSHR 4071/4885 |
| US-20140235565-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | COASY, SQOR, TST | CYP3A4 1922/4885MAPK1 3752/4885TSHR 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.