Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064866 | 1.00 | DAO (0.53) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30222224 | 0.74 | DAO (0.41) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11012748 | 0.74 | DAO (0.41) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11347910 | 0.74 | DAO (0.41) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3635550 | 0.74 | DAO (0.60) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3008864 | 0.74 | DAO (0.52) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6382774 | 0.74 | DAO (0.65) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28123905 | 0.71 | ALDH1A1 (0.59) | DAOKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3285152 | 0.71 | KMT2A (0.60) | DAOKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL5642053 | 0.70 | DAO (0.47) | DAOKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | WELLA GERMANY GMBH (DE) | 2026-05-28 | — | — | US | claimed |
| WO-2026104266-A1 | USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2026-05-21 | — | — | WO | claimed |
| EP-4739272-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | Wella Germany GmbH (DE) | 2026-05-13 | — | — | EP | claimed |
| EP-4731170-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | Wella Germany GmbH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | WELLA GERMANY GMBH (DE) | 2026-03-03 | — | — | US | claimed |
| US-20250057874-A1 | SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-20 | — | — | US | claimed |
| WO-2025031867-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | WELLA GERMANY GMBH (DE) | 2025-02-13 | — | — | WO | claimed |
| CN-119345488-A | Multifunctional vascular stent releasing double physiotherapy gases and preparation method thereof | 东莞市人民医院 | 2025-01-24 | — | — | CN | claimed |
| WO-2025008339-A1 | OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2025-01-09 | — | — | WO | claimed |
| WO-2024258183-A1 | SKIN SOOTHING OR ANTI-INFLAMMATORY COMPOSITION COMPRISING METAL-PHENOLIC COMPLEX AND MELANIN OR PRECURSOR THEREOF | 코스맥스 주식회사 | 2024-12-19 | — | — | WO | claimed |
| EP-0573205-A2 | Acidic post-treatment of hair dyed with dihydroxyindole | Bristol-Myers Squibb Company (US) | 1993-12-08 | — | — | EP | claimed |
| WO-1993013745-A1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| WO-1993013744-A1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | claimed |
| US-5011500-A | Developing with source of iodide ions and hydrogen peroxide, nitrite source and oxidizing agents; multicompartment kit; oxidation system; color- and washfast | L'OREAL (FR) | 1991-04-30 | — | — | US | claimed |
| EP-0166183-B1 | USE OF HYDROXYINDOLE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING THE BLOOD PRESSURE | MERCK PATENT GmbH (DE) | 1990-10-03 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| EP-0342034-A2 | Process for dyeing hair by the sequential treatment with metal ion containing composition and dye composition containing 5,6-dihydroxyindole-2-carboxylic acid | Bristol-Myers Squibb Company (US) | 1989-11-15 | — | — | EP | claimed |
| EP-0335477-A2 | The use of N-substituted-5,6-dihydroxyindoles as a hair coloring agent | Bristol-Myers Squibb Company (US) | 1989-10-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | PHOSPHO1, ALDH7A1, AASDHPPT | DAO 27/4885KDM4E 1524/4885ALDH1A1 173/4885 |
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | DEGS1, SGMS1, FABP4 | DAO 4064/4885KDM4E 3739/4885ALDH1A1 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.