Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163743 | 0.75 | KDM4E (0.52) | DAOKDM4EMCL1KMT2AMEN1 | |
| SCHEMBL154592 | 0.74 | KMT2A (0.55) | DAOSLC6A2TP53KDM4EMCL1 | |
| SCHEMBL49098 | 0.74 | DAO (0.53) | DAOSLC6A2KDM4ETSHRMCL1 | |
| SCHEMBL31064866 | 0.74 | DAO (0.53) | DAOSLC6A2KDM4ETSHRMCL1 | |
| SCHEMBL7678437 | 0.74 | SLC6A2 (0.44) | DAOSLC6A2TP53KDM4EHDAC1 | |
| SCHEMBL29378766 | 0.74 | KMT2A (0.55) | DAOSLC6A2TP53KDM4EMCL1 | |
| SCHEMBL6114342 | 0.73 | SLC6A2 (0.43) | DAOSLC6A2TP53KDM4EHDAC1 | |
| SCHEMBL3973543 | 0.73 | SLC6A2 (0.43) | DAOSLC6A2TP53KDM4EHDAC1 | |
| SCHEMBL3229178 | 0.73 | SLC6A2 (0.43) | DAOSLC6A2TP53KDM4EHDAC1 | |
| SCHEMBL18525155 | 0.73 | SLC6A2 (0.43) | DAOSLC6A2TP53KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295178-A | Method for improving color durability of artificially colored hair | 莱雅公司 | 2020-06-16 | — | — | CN | disclosed |
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| CN-101468964-B | Processes for producing indole compound | NISSAN CHEMICAL IND LTD | 2011-05-11 | — | — | CN | disclosed |
| US-20100197938-A1 | Process for producing indole compoud | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| CN-100577659-C | Processes for producing indole compound | NISSAN CHEMICAL IND LTD | 2010-01-06 | — | — | CN | disclosed |
| CN-101468964-A | Processes for producing indole compound | NISSAN CHEMICAL IND LTD (JP) | 2009-07-01 | — | — | CN | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20070083053-A1 | Process for producing indole compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| CN-1896075-A | Processes for producing indole compound | NISSAN CHEMICAL IND LTD (JP) | 2007-01-17 | — | — | CN | disclosed |
| CN-1286832-C | Process for producing indole compound | NISSAN CHEMICAL IND LTD (JP) | 2006-11-29 | — | — | CN | disclosed |
| EP-1658280-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AstraZeneca AB (SE) | 2006-05-24 | — | — | EP | disclosed |
| CN-1646522-A | Process for producing indole compound | NISSAN CHEMICAL IND LTD (JP) | 2005-07-27 | — | — | CN | disclosed |
| WO-2005014582-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197938-A1 | Process for producing indole compoud | IDO1, IDO2, NOS2 | DAO 93/4885SLC6A2 774/4885TP53 2600/4885 |
| US-20070083053-A1 | Process for producing indole compound | IDO2, IDO1, TDO2 | DAO 105/4885SLC6A2 974/4885TP53 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.