SCHEMBL49103

SCHEMBL49103

CO[Si](C)(OC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CA4 P22748 2/20 0.39
TSHR P16473 4/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
POLB P06746 2/20 0.34
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LTA4H P09960 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505641 0.97 ESR1 (0.39) ESR1ESR2CA4TSHRCA12
SCHEMBL15690303 0.95 ESR1 (0.38) ESR1ESR2CA4TSHRCA12
SCHEMBL8830315 0.93 ESR1 (0.37) ESR1ESR2CA4TSHRCA12
SCHEMBL15455618 0.91 ESR1 (0.35) ESR1ESR2CA4TSHRPOLB
SCHEMBL7601773 0.90 ESR1 (0.38) ESR1ESR2CA4TSHRCA12
SCHEMBL28979153 0.89 ESR1 (0.34) ESR1ESR2CA4TSHR
SCHEMBL10609352 0.87 ESR1 (0.37) ESR1ESR2CA4TSHRCA12
SCHEMBL18094271 0.87 ESR1 (0.37) ESR1ESR2CA4TSHRCA12
SCHEMBL30003108 0.87 ESR1 (0.37) ESR1ESR2CA4TSHRCA12
SCHEMBL2284805 0.85 ESR1 (0.35) ESR1ESR2CA4TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10850 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037202-A Silicone resin modified waterproof material, preparation method and application thereof 宁波润禾高新材料科技股份有限公司 2026-05-15 CN claimed
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE MEGA P&C ADVANCED MAT SHANGHAI CO LTD (CN) 2026-04-30 US claimed
EP-4015592-B1 CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES EVONIK OPERATIONS GMBH (DE) 2026-03-18 EP claimed
CN-121574290-A Preparation method of ultra-high-toughness 4-methyl-1-pentene/alpha-olefin copolymer 万华化学集团股份有限公司 2026-02-27 CN claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
EP-4653505-A1 COATING COMPOSITION, MATERIAL PRODUCT THEREOF, KIT, AND USE METHOD Mega P&C Advanced Materials (Shanghai) Co., Ltd. (CN) 2025-11-26 EP claimed
US-20250353967-A1 CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-20 US claimed
EP-4649356-A1 UNDERLAYER AND METHODS FOR EUV LITHOGRAPHY Brewer Science, Inc. (US) 2025-11-19 EP claimed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP claimed
US-4525421-A POLYSILOXANES, POLYETHERS, POLYEDOXIDES, POLYETHERSILOXANES KABUSHIKI KAISHA SUWA SEIKOSHA (JP) 1985-06-25 US claimed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP claimed
US-4500600-A GAMMAAMINOPROPYLTRIMETHOXYSILANE AND ANOTHER ALKOXYSILANE OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-02-19 US claimed
US-4309557-A Process for the preparation of alkyl and aryl substituted oligosiloxanes suitable for use as diffusion pump oils NUSIL RESEARCH (US) 1982-01-05 US claimed
US-4179537-A ALKOXYSILANES, SUBSTITUTED ALKOXYSILANES RYKOWSKI JOHN J 1979-12-18 US claimed
US-4141926-A Method for preparing epoxy-modified silicon resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1979-02-27 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed
US-4030813-A Control element having liquid layer attainable to geometrically uneven state in response to electrical signal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-06-21 US claimed
US-3959242-A MOLD RELEASE SURFACE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US claimed