Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003108 | 1.00 | ESR1 (0.37) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL18094271 | 1.00 | ESR1 (0.37) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL7601773 | 0.98 | ESR1 (0.38) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL25507022 | 0.94 | ESR1 (0.33) | ESR1ESR2CA4TSHR | |
| SCHEMBL20143197 | 0.92 | ESR1 (0.32) | ESR1ESR2CA4 | |
| SCHEMBL14193864 | 0.88 | ESR1 (0.35) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL49103 | 0.87 | ESR1 (0.41) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL8440982 | 0.86 | ESR1 (0.34) | ESR1ESR2CA4TSHR | |
| SCHEMBL9505641 | 0.85 | ESR1 (0.39) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL8437442 | 0.85 | ESR1 (0.33) | ESR1ESR2CA4TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139234-B1 | RESIN COMPOSITION | KABUSHIKI KAISHA TOSHIBA (JP) | 1989-11-29 | — | — | EP | disclosed |
| US-4599155-A | POLYORTHOESTERS;SHRINKAGE INHIBITION;NONCRACKING;COATINGS | KABUSHIKI KAISHA TOSHIBA (JP) | 1986-07-08 | — | — | US | disclosed |
| EP-0139234-A2 | Resin composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-05-02 | — | — | EP | disclosed |