Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003108 | 1.00 | ESR1 (0.37) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL10609352 | 1.00 | ESR1 (0.37) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL7601773 | 0.98 | ESR1 (0.38) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL25507022 | 0.94 | ESR1 (0.33) | ESR1ESR2CA4TSHR | |
| SCHEMBL20143197 | 0.92 | ESR1 (0.32) | ESR1ESR2CA4 | |
| SCHEMBL14193864 | 0.88 | ESR1 (0.35) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL49103 | 0.87 | ESR1 (0.41) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL8440982 | 0.86 | ESR1 (0.34) | ESR1ESR2CA4TSHR | |
| SCHEMBL9505641 | 0.85 | ESR1 (0.39) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL8437442 | 0.85 | ESR1 (0.33) | ESR1ESR2CA4TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994711-B2 | Condensation-curable silicone composition and a semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-06-12 | — | — | US | disclosed |
| US-9862803-B2 | Branched organopolysiloxane and a method for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-9587075-B2 | Addition-curable silicone composition and a semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160304673-A1 | ADDITION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160304675-A1 | BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160280959-A1 | CONDENSATION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |