SCHEMBL9505641

SCHEMBL9505641

CO[Si](C)(OC)c1ccccc1.[SiH4]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TSHR P16473 2/20 0.36
NQO2 P16083 2/20 0.33
POLB P06746 2/20 0.33
ALDH1A1 P00352 4/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49103 0.97 ESR1 (0.41) ESR1ESR2CA1CA2CA4
SCHEMBL15690303 0.92 ESR1 (0.38) ESR1ESR2CA1CA2CA4
SCHEMBL8830315 0.90 ESR1 (0.37) ESR1ESR2CA1CA2CA4
SCHEMBL15455618 0.88 ESR1 (0.35) ESR1ESR2CA4TSHRPOLB
SCHEMBL7601773 0.87 ESR1 (0.38) ESR1ESR2CA1CA2CA4
SCHEMBL28979153 0.86 ESR1 (0.34) ESR1ESR2CA4TSHR
SCHEMBL10609352 0.85 ESR1 (0.37) ESR1ESR2CA1CA2CA4
SCHEMBL18094271 0.85 ESR1 (0.37) ESR1ESR2CA1CA2CA4
SCHEMBL30003108 0.85 ESR1 (0.37) ESR1ESR2CA1CA2CA4
SCHEMBL2284805 0.83 ESR1 (0.35) ESR1ESR2CA4TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274101-B1 RESTORING STRANDED CONDUCTOR ELECTRICAL DISTRIBUTION CABLE DOW CORNING CORPORATION (US) 1993-06-09 EP disclosed
US-4766011-A TREATING INTERSTICLES WITH AROMATIC RADICAL CONTAINING SILANE DOW CORNING CORPORATION (US) 1988-08-23 US disclosed
EP-0274101-A2 Restoring stranded conductor electrical distribution cable DOW CORNING CORPORATION (US) 1988-07-13 EP disclosed