Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901005 | 0.83 | TP53 (0.60) | RAB9AALDH1A1NPC1HPGDKDM4E | |
| SCHEMBL10064823 | 0.81 | MGLL (0.56) | RAB9AALDH1A1NPC1HPGDKDM4E | |
| SCHEMBL1105447 | 0.79 | APP (0.69) | RAB9AALDH1A1NPC1HPGDKDM4E | |
| SCHEMBL6859827 | 0.76 | CA2 (0.63) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL8052920 | 0.76 | CA2 (0.63) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3679894 | 0.76 | ALDH1A1 (0.78) | RAB9AALDH1A1NPC1HPGDKDM4E | |
| SCHEMBL4913678 | 0.76 | PTPN1 (0.60) | ALDH1A1NPC1HPGDKDM4ETP53 | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL2878009 | 0.76 | ALDH1A1 (0.54) | RAB9AALDH1A1NPC1HPGDKDM4E | |
| SCHEMBL2890 | 0.75 | CA9 (0.53) | ALDH1A1SMN1; SMN2PKMMAPTGAA | |
| Toluene SCHEMBL9257721 | 0.74 | CA9 (0.51) | ALDH1A1SMN1; SMN2PKMMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299041-A1 | HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299041-A1 | HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION | APP, BACE1, PSEN1 | RAB9A 2635/4885ALDH1A1 2700/4885NPC1 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.