Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | UBE2M | P61081 | 3/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924357 | 0.89 | ALDH1A1 (0.47) | ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4924450 | 0.88 | ACKR3 (0.48) | ALDH1A1GAAUBE2MDCUN1D1ACKR3 | |
| SCHEMBL4922893 | 0.88 | CCR5 (0.45) | UBE2MDCUN1D1LMNASMN1; SMN2 | |
| SCHEMBL4924883 | 0.88 | TSHR (0.49) | TSHRSMN1; SMN2ACKR3 | |
| SCHEMBL4916411 | 0.88 | CHRM3 (0.42) | LMNASMN1; SMN2 | |
| SCHEMBL4912989 | 0.88 | ACKR3 (0.45) | UBE2MDCUN1D1LMNASMN1; SMN2ACKR3 | |
| SCHEMBL4923492 | 0.88 | PPARG (0.46) | ALDH1A1TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL4924440 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C19GAAACKR3 | |
| SCHEMBL4923464 | 0.86 | POLB (0.48) | ALDH1A1GAAUBE2MDCUN1D1LMNA | |
| SCHEMBL4914291 | 0.86 | UBE2M (0.45) | UBE2MDCUN1D1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | L3MBTL1 1904/4885ALDH1A1 1255/4885USP2 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.