Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141577 | 0.88 | CASP8 (0.49) | CASP8LDHAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL417132 | 0.86 | AOC3 (0.47) | HPGDSAOC3BAZ2AGSK3BDYRK1A | |
| SCHEMBL13997973 | 0.86 | BAZ2A (0.52) | HPGDSAOC3BAZ2AGSK3BDYRK1A | |
| SCHEMBL2143075 | 0.85 | CASP8 (0.47) | CASP8LDHAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1247127 | 0.85 | LDHA (0.49) | CASP8LDHAKMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2516985 | 0.84 | BAZ2A (0.51) | HPGDSAOC3BAZ2AGSK3BDYRK1A | |
| SCHEMBL996815 | 0.83 | LDHA (0.51) | CASP8LDHAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL24362835 | 0.82 | CASP8 (0.45) | CASP8LDHAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3553602 | 0.82 | CASP8 (0.45) | CASP8LDHAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10037307 | 0.82 | BAZ2A (0.48) | BAZ2ACASP8LDHAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104853604-B | The composition of alcoxylates comprising agricultural chemicals and the amine of 2 isopropyl, 5 methyl hexane 1 | 巴斯夫欧洲公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-103717578-B | Fungicidal substituted 1- {2- [ 2-halo-4- (4-halophenoxy) phenyl ] -2-ethoxyethyl } -1H- [1,2,4] triazole compounds | 巴斯夫欧洲公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-103717579-B | Fungicidal substituted 1- {2- [ 2-halo-4- (4-halophenoxy) phenyl ] -2-alkoxy-2-cyclylethyl } -1H- [1,2,4] triazole compounds | 巴斯夫欧洲公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106029645-A | N-substituted imino heterocyclic compounds | 巴斯夫欧洲公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-103492378-B | Parasite killing pyrazole compound | 巴斯夫欧洲公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105682459-A | Composition comprising a pesticide and an amide | 巴斯夫欧洲公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-104411170-A | Adjuvant comprising a 2-propylheptylamine alkoxylate, sugar-based surfactant, and drift-control agent and/or humectant | BASF SE | 2015-03-11 | — | — | CN | disclosed |
| US-8106048-B2 | protozoal infestations in humans and animals, by bacteria, viruses or proteinaceous agents; neurological diseases or disorders; ischemia and/or reperfusion injury; 4-(4-Ethoxycarbonyl-4,5-dihydro-thiazol-2-yl)-piperidine-1-carboxylic acid t-butyl ester | 4SC AG (DE) | 2012-01-31 | — | — | US | disclosed |
| CN-101031567-B | Novel heterocyclic NF-kB inhibitors | 4SC Corp.,Ltd. (DE) | 2011-12-21 | — | — | CN | disclosed |
| US-7812041-B2 | Heterocyclic NF-κB inhibitors | 4SC AG (DE) | 2010-10-12 | — | — | US | disclosed |
| US-20100048583-A1 | Novel Heterocyclic NF-kB Inhibitors | 4SC AG (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20080261971-A1 | Novel Heterocyclic Nf-Kb Inhibitors | 4SC AG (DE) | 2008-10-23 | — | — | US | disclosed |
| CN-101031567-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2007-09-05 | — | — | CN | disclosed |
| CN-1972923-A | Piperidine derivatives as modulators of chemokine receptor ccr5 | ASTRAZENECA AB (SE) | 2007-05-30 | — | — | CN | disclosed |
| US-20060069102-A1 | Novel heterocyclic NF-kB inhibitors | 4 SC AG (DE) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048583-A1 | Novel Heterocyclic NF-kB Inhibitors | NFKBIA, NFKB2, NFRKB | HPGDS 2327/4885AOC3 1287/4885BAZ2A 1702/4885 |
| US-20080261971-A1 | Novel Heterocyclic Nf-Kb Inhibitors | NFKBIA, NFKB2, NFRKB | HPGDS 2176/4885AOC3 1551/4885BAZ2A 1189/4885 |
| US-20060069102-A1 | Novel heterocyclic NF-kB inhibitors | NFKBIA, NFKB2, NFRKB | HPGDS 2315/4885AOC3 1312/4885BAZ2A 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.