SCHEMBL4912663

SCHEMBL4912663

CCCCCCCCCCCCCCO[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 5/20 0.59
SLC2A1 P11166 1/20 0.54
MAPK1 P28482 1/20 0.53
LGALS8 O00214 1/20 0.46
LGALS3 P17931 1/20 0.46
LGALS4 P56470 1/20 0.46
GJB2 P29033 1/20 0.46
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
TNF P01375 1/20 0.40
CETP P11597 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8443464 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL736485 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL5029670 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL1134708 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL182764 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL9291634 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL23646744 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL4391706 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL8940690 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL258033 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269163-A1 Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis UNIVERSITY OF FUKUI (JP) 2008-10-30 US claimed
EP-1814559-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-08-08 EP claimed
WO-2006045050-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2006-04-27 WO claimed
EP-4349902-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
EP-4349900-A1 VULCANIZED RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
EP-4349901-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
WO-2024005029-A1 VULCANIZED RUBBER COMPOSITION FOR TIRES, AND TIRE 株式会社ブリヂストン 2024-01-04 WO disclosed
WO-2023243129-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE 株式会社ブリヂストン 2023-12-21 WO disclosed
US-20230040071-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2023-02-09 US disclosed
WO-2022254750-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2022-12-08 WO disclosed
WO-2022254751-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2022-12-08 WO disclosed
WO-2022254749-A1 VULCANIZED RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2022-12-08 WO disclosed
WO-2021124811-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2021-06-24 WO disclosed
EP-3495162-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2019-06-12 EP disclosed
CN-103124739-B A kind of new glucagon-like peptide-1 analogs, composition and use thereof BETTA PHARMACEUTICALS Co.,Ltd. (CN) 2015-11-25 CN disclosed
EP-2514407-A1 Stable non-aqueous pharmaceutical compositions Novo Nordisk A/S (DK) 2012-10-24 EP disclosed
US-20080269163-A1 Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis UNIVERSITY OF FUKUI (JP) 2008-10-30 US disclosed
EP-1814559-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-08-08 EP disclosed
WO-2006045050-A1 METHODS AND COMPOSITIONS FOR PROTECTING CELLS FROM ULTRASOUND-MEDIATED CYTOLYSIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269163-A1 Methods and Compositions for Protecting Cells from Ultrasound-Mediated Cytolysis GZMB, RNASE1, CASP3 GBA1 722/4885SLC2A1 2310/4885MAPK1 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.