SCHEMBL736485

SCHEMBL736485

CCCCCCCCCCO[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 5/20 0.59
SLC2A1 P11166 1/20 0.54
MAPK1 P28482 1/20 0.53
LGALS8 O00214 1/20 0.46
LGALS3 P17931 1/20 0.46
LGALS4 P56470 1/20 0.46
GJB2 P29033 1/20 0.46
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
TNF P01375 1/20 0.40
CETP P11597 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8443464 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL5029670 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL1134708 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL182764 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL9291634 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL23646744 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL4391706 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL8940690 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL258033 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3
SCHEMBL4912663 1.00 GBA1 (0.59) GBA1SLC2A1MAPK1LGALS8LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635746-B1 Extracting elementary bodies of Chlamydia with detergent and reducing agent to dissolve cytoplasmic material, separating outer membrane material, extracting with nonionic detergents and reducing agent, separating outer membrane antigen extract AVENTIS PASTEUR LIMITED (CA) 2003-10-21 US claimed
US-5286625-A Pretreatment with nitric acid and surfactant SEIKAGAKU CORPORATION (JP) 1994-02-15 US claimed
US-10548860-B2 HIF-1 modulator paint formulation and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-02-04 US disclosed
US-20190192452-A1 HIF-1 MODULATOR PAINT FORMULATION AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY 2019-06-27 US disclosed
US-10220009-B2 HIF-1 modulator paint formulation and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-03-05 US disclosed
US-20150196512-A1 HIF-1 Modulator Paint Formulation and Uses Thereof THE JOHNS HOPKINS UNIVERSITY 2015-07-16 US disclosed
WO-2014036414-A2 IRON CHELATORS AND USE THEREOF FOR REDUCING TRANSPLANT FAILURE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-03-06 WO disclosed
US-8137975-B2 Method for a rapid antibody-based analysis of platelet populations BECKMAN COULTER, INC. (US) 2012-03-20 US disclosed
EP-2215219-A1 METHOD FOR A RAPID ANTIBODY-BASED ANALYSIS OF PLATELET POPULATIONS Beckman Coulter, Inc. (US) 2010-08-11 EP disclosed
US-7674598-B2 Method for a fully automated monoclonal antibody-based extended differential BECKMAN COULTER, INC. (US) 2010-03-09 US disclosed
EP-1294422-B1 Medical System for Reducing Vascular Occlusions CORDIS CORP (US) 2010-02-24 EP disclosed
US-20030104073-A1 Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same CORDIS US CORP 2003-06-05 US disclosed
EP-1294422-A1 METHODS AND SYSTEMS FOR ENHANCING FLUID FLOW THROUGH AN OBSTRUCTED VASCULAR SITE Corazon Technologies, Inc. (US) 2003-03-26 EP disclosed
US-6533767-B2 Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same CORAZON TECHNOLOGIES, INC. 2003-03-18 US disclosed
US-6488671-B1 Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same CORAZON TECHNOLOGIES, INC. 2002-12-03 US disclosed
US-6451739-B1 ACTIVE QUATERNARY AMMONIUM COMPOUND CONCENTRATES SUCH AS MEPIQUAT OR CHLORMEQUAT AND AT LEAST ONE AUXILIARY SELECTED FROM ALKYLGLUCOSIDES, AND ALKYLSULFONATES OR ALKYLARYLSULFONATES BASF AKTIENGESELLSCHAFT (DE) 2002-09-17 US disclosed
US-20010039411-A1 Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same CORDIS US CORP 2001-11-08 US disclosed
WO-2001070320-A1 METHODS AND SYSTEMS FOR ENHANCING FLUID FLOW THROUGH AN OBSTRUCTED VASCULAR SITE CORAZON TECHNOLOGIES, INC. (US) 2001-09-27 WO disclosed
EP-1100329-A1 AQUEOUS GROWTH-REGULATING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2001-05-23 EP disclosed
WO-2000007445-A1 AQUEOUS GROWTH-REGULATING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2000-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104073-A1 Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same CA2, DUOX2, SMOX GBA1 896/4885SLC2A1 225/4885MAPK1 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.