Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612537 | 0.82 | OPRD1 (0.48) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL4941602 | 0.80 | OPRK1 (0.49) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL4615941 | 0.77 | OPRK1 (0.51) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL18038731 | 0.75 | OPRL1 (0.59) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL4911230 | 0.74 | TSHR (0.47) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL2242094 | 0.74 | OPRK1 (0.49) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL2246366 | 0.74 | OPRK1 (0.49) | OPRD1OPRK1ALDH1A1KMT2AMAPT | |
| SCHEMBL16423921 | 0.72 | SLC6A3 (0.44) | OPRD1OPRK1KMT2AOPRM1 | |
| SCHEMBL4913216 | 0.72 | TSHR (0.45) | OPRD1OPRK1TSHRALOX15TACR1 | |
| SCHEMBL16422916 | 0.72 | SLC6A3 (0.44) | OPRD1OPRK1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MCMURRAY GORDON | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MC4R, MC5R, GPR4 | OPRD1 191/4885OPRK1 182/4885ALDH1A1 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.