Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924875 | 0.81 | BRD4 (0.33) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4911096 | 0.73 | DHFR (0.40) | RAB9ASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL4912561 | 0.69 | MAOA (0.39) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3568443 | 0.65 | ADORA1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8756843 | 0.61 | ADORA2A (0.53) | SMN1; SMN2KDM4EALDH1A1KMT2AADORA2A | |
| SCHEMBL4914126 | 0.61 | CYP1A2 (0.35) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL4912323 | 0.61 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4909958 | 0.61 | ALOX15 (0.37) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL207641 | 0.61 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10876324 | 0.60 | CYP19A1 (0.41) | KDM4EMAPTKMT2ALTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | claimed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | claimed |
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | disclosed |
| US-20080092306-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-04-24 | — | — | US | disclosed |
| EP-1781241-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | disclosed |
| WO-2006026488-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, NOX5 | NPC1 4609/4885RAB9A 3674/4885SMN1; SMN2 4726/4885 |
| US-20080092306-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, KDM5A, NOX5 | NPC1 4609/4885RAB9A 3674/4885SMN1; SMN2 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.