SCHEMBL491408

SCHEMBL491408

C=C(C)C(=O)NC(=O)C=CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
GAA P10253 2/20 0.43
TSHR P16473 3/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
TGFBR1 P36897 1/20 0.38
HCAR2 Q8TDS4 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 2/20 0.37
NMT1 P30419 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
CREBBP Q92793 1/20 0.35
KMT2A Q03164 1/20 0.35
ALOX15 P16050 1/20 0.34
RECQL P46063 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491406 1.00 ALDH1A1 (0.43) ALDH1A1GAATSHRTP53EGLN1
SCHEMBL9550398 0.91 TGFBR1 (0.39) ALDH1A1GAATGFBR1TDP1
SCHEMBL28469499 0.82 ALDH1A1 (0.46) ALDH1A1GAATSHRTP53EGLN1
SCHEMBL15422359 0.80 TGFBR1 (0.35) ALDH1A1TGFBR1TDP1
SCHEMBL15422360 0.80 TGFBR1 (0.35) ALDH1A1TGFBR1TDP1
SCHEMBL28514326 0.75 ALDH1A1 (0.35) ALDH1A1TGFBR1TDP1
SCHEMBL1414999 0.75 ALDH1A1 (0.41) ALDH1A1TSHRTP53TGFBR1LMNA
Fumaric Acid SCHEMBL11664868 0.74 TSHR (0.39) ALDH1A1GAATSHRTP53EGLN1
Methacrylic Acid SCHEMBL6231224 0.74 ALDH1A1 (0.39) ALDH1A1TSHRTP53TGFBR1LMNA
Fumaric Acid SCHEMBL63722 0.73 TSHR (0.56) ALDH1A1GAATSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-8084110-B2 Glycoluril resin and polyol resin members XEROX CORPORATION (US) 2011-12-27 US claimed
US-8067139-B2 Resin mixture backing layer containing photoconductor XEROX CORPORATION (US) 2011-11-29 US claimed
EP-2237114-A1 Glycoluril resin and polyol resin members Xerox Corporation (US) 2010-10-06 EP claimed
EP-2237115-A1 Intermediate transfer member comprising a coating of a mxiture of glycoluril resin and polyol resin Xerox Corporation (US) 2010-10-06 EP claimed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248103-A1 RESIN MIXTURE BACKING LAYER CONTAINING PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248107-A1 GLYCOLURIL RESIN AND POLYOL RESIN MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100221651-A1 EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US claimed
EP-2224288-A2 Epoxy carboxyl resin mixture hole blocking layer photoconductors Xerox Corporation (US) 2010-09-01 EP claimed
US-7579126-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2009-08-25 US claimed
US-20080220350-A1 Hole blocking layer containing photoconductors XEROX CORPORATION 2008-09-11 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
US-20190270857-A1 PLANARIZATION COATING FOR FLEXIBLE PRINTED ELECTRONICS XEROX CORPORATION (US) 2019-09-05 US disclosed
US-20080008950-A1 Electrophotographic imaging member undercoat layers XEROX CORPORATION 2008-01-10 US disclosed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US disclosed