Sugi Predict

Sugi Predict / Compounds / Styrene

Styrene

Styrene

SCHEMBL4914892

C=C(C)C(=O)OC(O)CC.C=Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.41
▸ TSHR P16473 1/20 0.41
▸ MEN1 O00255 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ ELANE P08246 1/20 0.37
▸ HPGD P15428 2/20 0.35
▸ MAPT P10636 3/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ TAS1R3 Q7RTX0 1/20 0.35
▸ TAS1R1 Q7RTX1 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ ADORA3 P0DMS8 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ AKR1C3 P42330 1/20 0.34
▸ GLA P06280 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28298815 0.86 MEN1 (0.40) ALDH1A1TSHRMEN1KMT2AELANE
Phthalic Acid SCHEMBL27818266 0.84 ALDH1A1 (0.42) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL11394471 0.83 TSHR (0.45) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL5411290 0.83 TAS1R3 (0.42) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL7927920 0.82 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL27896138 0.82 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2AELANE
Styrene SCHEMBL27602216 0.82 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2AELANE
Acrylic Acid SCHEMBL11779134 0.81 TSHR (0.36) ALDH1A1TSHRLMNA
SCHEMBL11414241 0.81 TSHR (0.38) ALDH1A1TSHR
Styrene SCHEMBL18526988 0.81 ALDH1A1 (0.42) ALDH1A1TSHRMEN1KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524966-B Aqueous polymer dispersons for stabilizing actives 罗门哈斯公司 2017-01-18 — — CN disclosed
US-20120213996-A1 ALLERGEN-INHIBITING FIBERS SUZUKI TARO (JP) 2012-08-23 — — US disclosed
US-20080138311-A1 Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet SUZUKI TARO 2008-06-12 — — US disclosed
US-20050095222-A1 Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet SEKISUI CHEMICAL CO., LTD. (JP) 2005-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095222-A1 Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet CMA1, HLA-DRB1, ITCH ALDH1A1 4512/4885TSHR 4804/4885MEN1 4757/4885
US-20080138311-A1 Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet CMA1, HRH2, HLA-DRB1 ALDH1A1 4502/4885TSHR 4817/4885MEN1 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.