Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899003 | 0.81 | ALDH1A1 (0.74) | GPR139HPGDMAPTMEN1KMT2A | |
| SCHEMBL17291601 | 0.79 | LMNA (0.67) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL13998890 | 0.79 | HPGD (0.62) | HPGDLMNAALDH1A1L3MBTL1POLB | |
| SCHEMBL15571840 | 0.79 | LMNA (0.67) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL15116379 | 0.79 | MAPT (0.63) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL25336878 | 0.79 | MAPT (0.63) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL15131221 | 0.79 | MAPT (0.63) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL15571273 | 0.79 | LMNA (0.67) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL8445815 | 0.78 | GPR139 (0.55) | GPR139HPGDMAPTLMNACRHBP | |
| SCHEMBL5907646 | 0.78 | MAPT (0.62) | GPR139HPGDMAPTLMNACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080073221-A1 | Selective Splitting of Substituted Bisbenzylamides and Bisbenzylamines | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-27 | — | — | US | disclosed |
| EP-1853549-A1 | SELECTIVE SPLITTING OF SUBSTITUTED BISBENZYLAMIDES AND BISBENZYLAMINES | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087321-A1 | SELECTIVE SPLITTING OF SUBSTITUTED BISBENZYLAMIDES AND BISBENZYLAMINES | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-24 | — | — | WO | disclosed |