Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338044 | 1.00 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL5258381 | 0.98 | TSHR (0.42) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL10657097 | 0.95 | TSHR (0.41) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL13245112 | 0.91 | — | — | |
| SCHEMBL25223615 | 0.88 | HIF1A (0.41) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL28798179 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CNR1CNR2 | |
| SCHEMBL18215215 | 0.81 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL3304850 | 0.80 | — | — | |
| SCHEMBL5159311 | 0.80 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL13864131 | 0.80 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242362-B2 | Phosphazene compound, preparation method and use thereof | QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-02-08 | — | — | US | disclosed |
| US-20190315786-A1 | PHOSPHAZENE COMPOUND, PREPARATION METHOD AND USE THEREOF | QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | WAKAMOTO PHARMACEUTICAL CO., LTD (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1820799-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-3978097-A | INSECTICIDES, MITICIDES | SANDOZ LTD. (CH) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076760-A1 | 2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION | GABRA5, GABRA1, GABRB1 | TSHR 1671/4885FAAH 3283/4885TRPV1 284/4885 |
| US-20190315786-A1 | PHOSPHAZENE COMPOUND, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, WEE1, PLCB1 | TSHR 2407/4885FAAH 908/4885TRPV1 3736/4885 |
| US-11242362-B2 | Phosphazene compound, preparation method and use thereof | PHOSPHO1, WEE1, PLCB1 | TSHR 2407/4885FAAH 908/4885TRPV1 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.