Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922456 | 0.92 | ALDH1A1 (0.50) | MEN1KMT2ALMNASMN1; SMN2MCHR1 | |
| SCHEMBL4923562 | 0.92 | TSHR (0.54) | L3MBTL1ACKR3TSHRDRD2DRD3 | |
| SCHEMBL4917794 | 0.91 | LMNA (0.52) | L3MBTL1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL4923485 | 0.84 | ALDH1A1 (0.59) | ACKR3TSHRMEN1KMT2ALMNA | |
| SCHEMBL4920802 | 0.84 | SMN1; SMN2 (0.51) | TSHRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4917352 | 0.82 | SMN1; SMN2 (0.49) | TSHRDRD2DRD3MEN1KMT2A | |
| SCHEMBL4915790 | 0.80 | ACKR3 (0.46) | L3MBTL1ACKR3TSHRDRD2DRD3 | |
| SCHEMBL4922789 | 0.80 | TSHR (0.60) | L3MBTL1ACKR3TSHRMEN1KMT2A | |
| SCHEMBL14586598 | 0.79 | LMNA (0.55) | L3MBTL1ACKR3TSHRLMNASMN1; SMN2 | |
| SCHEMBL4918023 | 0.78 | TSHR (0.57) | ACKR3TSHRDRD2DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | L3MBTL1 1904/4885ACKR3 5/4885TSHR 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.