Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924427 | 1.00 | DRD2 (0.36) | DRD2HSD11B1RORCOPRL1OPRM1 | |
| SCHEMBL4921780 | 0.90 | GAA (0.39) | OPRL1OPRM1 | |
| SCHEMBL4916637 | 0.90 | GAA (0.39) | OPRL1OPRM1 | |
| SCHEMBL4924815 | 0.85 | SLC6A3 (0.42) | DRD2HSD11B1RORCOPRL1OPRM1 | |
| SCHEMBL4919417 | 0.75 | SLC6A3 (0.45) | DRD2HSD11B1RORCOPRL1 | |
| SCHEMBL4926309 | 0.75 | SLC6A3 (0.45) | DRD2HSD11B1RORCOPRL1 | |
| SCHEMBL4911239 | 0.74 | CNR2 (0.42) | — | |
| SCHEMBL4603488 | 0.71 | HSD11B1 (0.38) | HSD11B1RORCOPRM1 | |
| SCHEMBL4602863 | 0.71 | HSD11B1 (0.38) | HSD11B1RORCOPRM1 | |
| SCHEMBL2428686 | 0.71 | HSD11B1 (0.31) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MCMURRAY GORDON | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234280-A1 | Use of Mc4 Receptor Agonist Compounds | MC4R, MC5R, GPR4 | DRD2 511/4885HSD11B1 1631/4885RORC 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.