Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12528207 | 0.82 | KDM4E (0.65) | KDM4EGAALMNAMAPK11MAPK14 | |
| SCHEMBL4918738 | 0.82 | ALDH1A1 (0.46) | KDM4EGAALMNAMAPK11MAPK14 | |
| SCHEMBL17255733 | 0.82 | KDM4E (0.47) | KDM4EGAALMNANPC1RAB9A | |
| SCHEMBL5807693 | 0.81 | HTT (0.51) | KDM4EGAALMNANPC1OPRM1 | |
| SCHEMBL11435978 | 0.81 | LMNA (0.51) | LMNANPC1OPRM1ALDH1A1 | |
| SCHEMBL1817147 | 0.79 | CYP1A2 (0.59) | KDM4EPDE4BLMNARAB9AOPRM1 | |
| SCHEMBL4917993 | 0.78 | P2RY1 (0.46) | KDM4EGAAP2RY1LMNAOPRM1 | |
| SCHEMBL28674190 | 0.78 | PDE4B (0.45) | KDM4EPDE4BGAAP2RY1LMNA | |
| SCHEMBL28675292 | 0.78 | ALDH1A1 (0.52) | KDM4EPDE4BGAAP2RY1LMNA | |
| SCHEMBL3676529 | 0.77 | NPC1 (0.63) | KDM4ELMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269293-A1 | PYRAZOLE DERIVATIVES AS ANTI-PLATELET AND ANTI-THROMBOTIC AGENTS | PFIZER INC. | 2008-10-30 | — | — | US | disclosed |
| WO-2008023235-A1 | PYRAZOLE DERIVATIVES AS ANTI-PLATELET AND ANTI-THROMBOTIC AGENTS | PFIZER PRODUCTS INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| US-4217272-A | DYEING CELLULOSIC FIBERS | STERLING DRUG INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4153598-A | Monoazo and diazo colorants from aminoalkylanilines and bis(aminoalkyl)anilines | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269293-A1 | PYRAZOLE DERIVATIVES AS ANTI-PLATELET AND ANTI-THROMBOTIC AGENTS | P2RY1, P2RY11, P2RX7 | KDM4E 3700/4885PDE4B 341/4885GAA 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.