Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859963 | 0.82 | LTA4H (0.44) | CA12CA1CA2CA4CA7 | |
| SCHEMBL3246008 | 0.79 | IDO1 (0.46) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL3296809 | 0.78 | IDO1 (0.61) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL64882 | 0.77 | CA1 (0.42) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL18706055 | 0.76 | HTR7 (0.42) | CHRM2ALDH1A1GAAMAPTCA12 | |
| SCHEMBL2411279 | 0.76 | LMNA (0.38) | ALDH1A1MAPTL3MBTL1ATMCA12 | |
| SCHEMBL2413817 | 0.76 | KMT2A (0.38) | ALDH1A1GAAMAPTCA2MAPK1 | |
| SCHEMBL1526352 | 0.76 | CA1 (0.41) | ALDH1A1MAPTL3MBTL1CA12CA1 | |
| SCHEMBL4586248 | 0.76 | TAAR1 (0.41) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL28069112 | 0.76 | CA1 (0.41) | IDO1TAAR1CHRM2CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7453009-B2 | Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | GPR119, HACL2, HCAR2 | IDO1 3560/4885TAAR1 3096/4885CHRM2 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.