Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133575 | 0.86 | ADORA3 (0.50) | TLR7ADORA1LMNAHTTPAK1 | |
| SCHEMBL3136748 | 0.81 | LMNA (0.58) | TLR7ADORA1LMNAHTTPAK1 | |
| SCHEMBL3137133 | 0.77 | XDH (0.59) | HTTADORA3ADORA2ABRAFXDH | |
| SCHEMBL3141427 | 0.76 | ADORA3 (0.46) | HTTADORA3BRAFXDHCCNB2 | |
| SCHEMBL3136203 | 0.68 | CDK2 (0.40) | HSD17B10ALDH1A1BRAFXDHCDK2 | |
| SCHEMBL4534389 | 0.68 | CDK2 (0.40) | ADORA1ADORA3ADORA2AALDH1A1BRAF | |
| SCHEMBL1233712 | 0.68 | PDPK1 (0.59) | LMNABRAFXDHCDK1CCNB1 | |
| SCHEMBL3137199 | 0.68 | DPP4 (0.56) | ADORA3ALDH1A1BRAFXDHCDK2 | |
| SCHEMBL3133570 | 0.68 | TLR7 (0.49) | TLR7LMNAHTTPAK1PKM | |
| SCHEMBL16146850 | 0.67 | LMNA (0.54) | ADORA1LMNAHTTPAK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139583-A1 | PHOSPHODIESTERASE 4 INHIBITORS | TEHIM ASHOK | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139583-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE3B, PDE3A | TLR7 4771/4885ADORA1 954/4885HTR2B 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.