Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034358 | 0.85 | BRD4 (0.62) | PKMPTGDR2KCNA5LTA4HL3MBTL1 | |
| SCHEMBL14007193 | 0.83 | EPHX2 (0.52) | PTGDR2KCNA5LTA4HL3MBTL1TSHR | |
| SCHEMBL4248991 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GAAMAPTEPHX2 | |
| SCHEMBL14007242 | 0.78 | EPHX2 (0.76) | PTGDR2MEN1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL4665263 | 0.77 | BRD4 (0.51) | KDM6BKDM5CKDM2AKDM3AMEN1 | |
| SCHEMBL4251833 | 0.76 | BRD4 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL20726668 | 0.75 | PARP10 (0.51) | KCNA5L3MBTL1PARP10ALDH1A1SMN1; SMN2 | |
| SCHEMBL89177 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAHTTEPHX2 | |
| SCHEMBL3161296 | 0.74 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL1285278 | 0.73 | PKM (1.00) | PKML3MBTL1PARP10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | ELDRUP ANNE BETTINA | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | EPHX1, EPHX2, DOHH | PKM 1847/4885PTGDR2 326/4885KDM6B 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.