Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.81 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.81 |
| ▸ | DRD2 | P14416 | 2/20 | 0.81 |
| ▸ | DRD1 | P21728 | 2/20 | 0.81 |
| ▸ | DRD4 | P21917 | 2/20 | 0.81 |
| ▸ | DRD5 | P21918 | 2/20 | 0.81 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.81 |
| ▸ | DRD3 | P35462 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | APEX1 | P27695 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL28531201 | 1.00 | KDM4E (0.81) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL30379944 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL496657 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL16685137 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29375089 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL9166387 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29362033 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL18159501 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL8505 | 0.90 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL23704750 | 0.88 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119881040-A | Photoelectrochemical sensor of Z-type nano heterojunction, and preparation method and application thereof | 安徽工程大学 | 2025-04-25 | — | — | CN | claimed |
| CN-114392245-B | Dopamine-embedded nano-selenium assembled compound and preparation method thereof | 自然资源部第三海洋研究所 | 2023-10-10 | — | — | CN | claimed |
| CN-114392236-B | Co-doped dopamine-nano elemental selenium composition and preparation method thereof | 自然资源部第三海洋研究所 | 2023-06-27 | — | — | CN | claimed |
| US-20220416230-A1 | ELECTRODE MATERIALS, AND METHODS OF MANUFACTURING AND USE THEREOF | JINAN UNIVERSITY (CN) | 2022-12-29 | — | — | US | claimed |
| CN-114392245-A | Dopamine-embedded nano-selenium assembly compound and preparation method thereof | 自然资源部第三海洋研究所 | 2022-04-26 | — | — | CN | claimed |
| CN-114392236-A | Co-doped dopamine-nano elemental selenium composition and preparation method thereof | 自然资源部第三海洋研究所 | 2022-04-26 | — | — | CN | claimed |
| CN-114291965-A | System for ecological innocent treatment of domestic sewage | 内江师范学院 | 2022-04-08 | — | — | CN | claimed |
| CN-110987833-A | Glucose biosensor material, preparation method and application | 河北农业大学 | 2020-04-10 | — | — | CN | claimed |
| CN-105136888-B | A kind of glucose oxidase electrode based on Graphene derivative and preparation method thereof | 南京理工大学 | 2018-05-01 | — | — | CN | claimed |
| CN-106018533-A | Molecularly imprinted electrochemical sensor for detecting trace sulfamonomethoxine | 肇庆学院 | 2016-10-12 | — | — | CN | claimed |
| CN-105136888-A | Graphene derivative based glucose oxidase electrode and preparation method thereof | UNIV NANJING SCIENCE & TECH | 2015-12-09 | — | — | CN | claimed |
| CN-103272499-A | Dopamine-polyethersulfone composite membrane and preparation method thereof | UNIV TIANJIN | 2013-09-04 | — | — | CN | claimed |
| US-20260091004-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | INBRAIN PHARMA (FR) | 2026-04-02 | — | — | US | disclosed |
| US-12482814-B2 | Electrode materials, and methods of manufacturing and use thereof | JINAN UNIVERSITY (CN) | 2025-11-25 | — | — | US | disclosed |
| EP-4586995-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | InBrain Pharma (FR) | 2025-07-23 | — | — | EP | disclosed |
| CN-120064414-A | Preparation method and application of streptomycin electrochemical bionic imprinting aptamer sensor | 河南科技大学 | 2025-05-30 | — | — | CN | disclosed |
| EP-1178994-A1 | IMPROVED PROCESS FOR PHOSPHORYLATION AND COMPOUNDS PRODUCED BY THIS PROCESS | Swig Pty. Ltd. (AU) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069865-A1 | IMPROVED PROCESS FOR PHOSPHORYLATION AND COMPOUNDS PRODUCED BY THIS PROCESS | SWIG PTY LTD (AU) | 2000-11-23 | — | — | WO | disclosed |
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | disclosed |
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260091004-A1 | PHARMACEUTICAL INJECTABLE SOLUTION COMPRISING DOPAMINE | PARK7, SNCA, SLC6A3 | KDM4E 3224/4885MAPT 578/4885MAPK1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.