SCHEMBL4918263

SCHEMBL4918263

C=CC(=O)NC(O)(O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.41
FGFR4 P22455 1/20 0.41
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TGM2 P21980 2/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL976113 0.87
SCHEMBL1420931 0.76 ALDH1A1 (0.41) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL27961654 0.76 ALDH1A1 (0.43) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL2702042 0.72
SCHEMBL1548739 0.72
SCHEMBL5138580 0.72 ALDH1A1 (0.40) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL2943903 0.72
SCHEMBL11304863 0.72 ALDH1A1 (0.41) TSHRALDH1A1FGFR4MAPK1TDP1
Acrylamide SCHEMBL998819 0.71 ALDH1A1 (0.50) TSHRALDH1A1FGFR4MAPK1TDP1
SCHEMBL3315750 0.70 ALDH1A1 (0.43) TSHRALDH1A1FGFR4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2703411-B1 NANOPARTICLES CONTAINING PH-RESPONSIVE PEPTIDE TAIHO PHARMACEUTICAL CO LTD (JP) 2017-10-11 EP disclosed
WO-2016200343-A1 AQUEOUS, THICKENED AND TRANSPARENT BLEACHING COMPOSITIONS HAYAT KIMYA SANAYI ANONIM SIRKETI (TR) 2016-12-15 WO disclosed
US-9186389-B2 Nanoparticles containing pH-responsive peptide TAIHO PHARMACEUTICAL CO., LTD. (JP) 2015-11-17 US disclosed
US-20150147369-A1 Personal Care Compositions That Deposit Solid Hydrophilic Benefit Agents PROCTER & GAMBLE (US) 2015-05-28 US disclosed
EP-2703411-A1 NANOPARTICLES CONTAINING pH-RESPONSIVE PEPTIDE Taiho Pharmaceutical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140044778-A1 NANOPARTICLES CONTAINING pH-RESPONSIVE PEPTIDE TAIHO PHARMACEUTICAL CO., LTD. (JP) 2014-02-13 US disclosed
US-20130259913-A1 PARTICLES AND PARTICLE GAS SATURATED SOLUTION PROCESSES FOR MAKING SAME THE PROCTER & GAMBLE COMPANY 2013-10-03 US disclosed
WO-2012141946-A1 PARTICLES AND PARTICLE GAS SATURATED SOLUTION PROCESSES FOR MAKING SAME THE PROCTER & GAMBLE COMPANY (US) 2012-10-18 WO disclosed
US-8263058-B2 Personal care compositions that deposit hydrophilic benefit agents THE PROCTER & GAMBLE COMPANY (US) 2012-09-11 US disclosed
US-20080033058-A1 Personal care compositions that deposit hydrophilic benefit agents STELLA QING 2008-02-07 US disclosed
EP-0950392-B1 Non-sweating lipsticks PROCTER & GAMBLE (US) 2004-12-29 EP disclosed
US-6325995-B1 Lipsticks compositions containing association structures THE PROCTER & GAMBLE COMPANY 2001-12-04 US disclosed
EP-0725620-B1 NON-SWEATING LIPSTICKS PROCTER & GAMBLE (US) 2001-03-14 EP disclosed
EP-0950392-A1 Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1999-10-20 EP disclosed
US-5843407-A Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1998-12-01 US disclosed
EP-0660696-B1 LIPSTICKS PROCTER & GAMBLE (US) 1997-01-08 EP disclosed
EP-0725620-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1996-08-14 EP disclosed
EP-0660696-A1 LIPSTICKS. PROCTER & GAMBLE (US) 1995-07-05 EP disclosed
WO-1995011000-A1 NON-SWEATING LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1995-04-27 WO disclosed
WO-1994006400-A1 LIPSTICKS THE PROCTER & GAMBLE COMPANY (US) 1994-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080033058-A1 Personal care compositions that deposit hydrophilic benefit agents CUTA, DSG1, PLOD3 TSHR 3774/4885ALDH1A1 2022/4885FGFR4 2243/4885
US-20150147369-A1 Personal Care Compositions That Deposit Solid Hydrophilic Benefit Agents CUTA, LIPA, DSG1 TSHR 2935/4885ALDH1A1 2116/4885FGFR4 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.