Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919160 | 0.86 | GAA (0.36) | GAAALDH1A1KMT2A | |
| SCHEMBL20233444 | 0.82 | GAA (0.34) | GAAALDH1A1KMT2A | |
| SCHEMBL4915631 | 0.82 | POLB (0.38) | GAAPOLBALDH1A1KMT2A | |
| SCHEMBL29508220 | 0.77 | KMT2A (0.36) | KMT2A | |
| SCHEMBL27292832 | 0.77 | GAA (0.34) | GAAALDH1A1KMT2A | |
| SCHEMBL12258958 | 0.76 | OPRM1 (0.39) | — | |
| SCHEMBL12258966 | 0.76 | TRPV1 (0.35) | — | |
| SCHEMBL22959400 | 0.75 | HDAC1 (0.34) | — | |
| SCHEMBL22960798 | 0.75 | HDAC1 (0.34) | — | |
| SCHEMBL21431166 | 0.75 | HDAC6 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269065-A1 | Conformationally Constrained Analytical Probes | SYNTRIX BIOSYSTEMS, INC. (US) | 2008-10-30 | — | — | US | disclosed |