SCHEMBL4920437

SCHEMBL4920437

c1ccc2c(c1)OCCOCCOCCOCCOCCOCCOCCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 1.00
▸ SMN1; SMN2 Q16637 3/20 1.00
▸ CRHBP P24387 2/20 1.00
▸ CRHR2 Q13324 2/20 1.00
▸ HTT P42858 2/20 1.00
▸ ITGB2 P05107 1/20 0.82
▸ ICAM1 P05362 1/20 0.82
▸ ITGAL P20701 1/20 0.82
▸ GAA P10253 2/20 0.65
▸ ABCG2 Q9UNQ0 1/20 0.55
▸ KDM4E B2RXH2 3/20 0.55
▸ MAPT P10636 5/20 0.54
▸ BLM P54132 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.50
▸ KMT2A Q03164 1/20 0.42
▸ MAOA P21397 1/20 0.39
▸ MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676131 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505395 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL35765 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL10025196 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL687476 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL23658043 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL16076325 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL76331 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11591558 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL10425464 1.00 LMNA (1.00) LMNASMN1; SMN2CRHBPCRHR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260142234-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CROWN ETHER BASED COMPOUNDS ENEVATE CORP (US) 2026-05-21 — — US claimed
CN-122011416-A Organosilicon supermolecular elastomer based on crown ether host-guest effect crosslinking and preparation method thereof 山东大学 2026-05-12 — — CN claimed
US-20260024780-A1 MEMBRANE ELECTRODE ASSEMBLY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2026-01-22 — — US claimed
US-20260024793-A1 MEMBRANE ELECTRODE ASSEMBLY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2026-01-22 — — US claimed
CN-120118117-A Sodium acetate-based nano water purifying agent and preparation method thereof 广州市豫泉净水材料有限公司 2025-06-10 — — CN claimed
CN-119350615-A Heterocyclic aramid nanofiber membrane and preparation method thereof 清华大学 2025-01-24 — — CN claimed
US-20240154132-A1 MEMBRANE ELECTRODE ASSEMBLY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-05-09 — — US claimed
US-20240128469-A1 MEMBRANE ELECTRODE ASSEMBLY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2024-04-18 — — US claimed
US-11923545-B2 Crown ethers as additives for silicon-based Li-ion batteries ENEVATE CORPORATION (US) 2024-03-05 — — US claimed
CN-114317046-B Fuel additive containing crown ether metal complex and preparation method and application thereof 天津悦泰石化科技有限公司 2023-08-15 — — CN claimed
CN-111410940-B Additive for drilling fluid, preparation method and application of additive for drilling fluid 中国石油化工股份有限公司 2022-05-03 — — CN claimed
CN-114395334-A Preparation method of high-water-resistance instant adhesive 宁波百仕高联合工业有限公司 2022-04-26 — — CN claimed
CN-114317046-A Fuel additive containing crown ether metal complex and preparation method and application thereof 天津悦泰石化科技有限公司 2022-04-12 — — CN claimed
US-20260142234-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CROWN ETHER BASED COMPOUNDS ENEVATE CORP (US) 2026-05-21 — — US disclosed
CN-122011416-A Organosilicon supermolecular elastomer based on crown ether host-guest effect crosslinking and preparation method thereof 山东大学 2026-05-12 — — CN disclosed
US-20260074240-A1 MEMBRANE ELECTRODE ASSEMBLY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2026-03-12 — — US disclosed
CN-111050883-A Moisture-absorbing material 夏普株式会社 2020-04-21 — — CN disclosed
US-8242162-B2 Sensor group attachec to imide of aromatictetracarboxylic dianhydride; aromatic core may be anthracene, phenanthrene, perylene, or benzo[e]pyrene; sensor groups include crown ethers, aryl amines, porphyrins, and phenylboronic acid; detecting nitroaromatic explosives and chemical warfare agents OHIO AEROSPACE INSTITUTE (US) 2012-08-14 — — US disclosed
US-20080242870-A1 FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE OHIO AEROSPACE INSTITUTE (US) 2008-10-02 — — US disclosed
US-6323163-B1 PERFLUOROPOLYOXYALKYLENE CHAIN HAVING AVERAGE MOLECULAR WEIGHT OF 800 OR MORE, CONTAINING CYCLIC POLYETHER GROUP HAVING AT LEAST 4 OXYGEN ATOMS, ALSO HAVING AMIDE, SULFONAMIDE, ETHER OR ESTER LINKAGE BETWEEN CHAIN AND CYCLIC GROUP HITACHI, LTD. (JP) 2001-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260142234-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CROWN ETHER BASED COMPOUNDS SLC8A1, RPS4X, LBR LMNA 1474/4885SMN1; SMN2 947/4885CRHBP 3297/4885
US-20260024793-A1 MEMBRANE ELECTRODE ASSEMBLY LNPK, VAMP8, EMC2 LMNA 1389/4885SMN1; SMN2 1173/4885CRHBP 4100/4885
US-20080242870-A1 FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE AHR, PAH, ALK LMNA 17/4885SMN1; SMN2 3891/4885CRHBP 1640/4885
US-20260024780-A1 MEMBRANE ELECTRODE ASSEMBLY KCNJ8, KCNN4, KCNN2 LMNA 1065/4885SMN1; SMN2 2018/4885CRHBP 3761/4885
US-20260074240-A1 MEMBRANE ELECTRODE ASSEMBLY EMC2, EMC1, EPCAM LMNA 2273/4885SMN1; SMN2 2764/4885CRHBP 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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