SCHEMBL49220

SCHEMBL49220

Nc1nccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 1.00
NCF1 P14598 2/20 1.00
F12 P00748 2/20 1.00
NOS3 P29474 1/20 1.00
NOS1 P29475 1/20 1.00
NOS2 P35228 1/20 1.00
BACE1 P56817 1/20 1.00
CYP2A6 P11509 2/20 0.56
ROCK1 Q13464 4/20 0.51
PLG P00747 2/20 0.50
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAP4K4 O95819 1/20 0.47
CYP3A4 P08684 3/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377365 1.00 PLAU (1.00) PLAUNCF1F12NOS3NOS1
SCHEMBL28116864 0.98 PLAU (0.95) PLAUNCF1F12NOS3NOS1
Iodide SCHEMBL29988059 0.98 PLAU (0.95) PLAUNCF1F12NOS3NOS1
Hydrochloric Acid SCHEMBL509104 0.98 PLAU (0.95) PLAUNCF1F12NOS3NOS1
Formic Acid SCHEMBL30738145 0.88 F12 (0.78) PLAUNCF1F12NOS3NOS1
Quinoline SCHEMBL28251904 0.87 NCF1 (0.75) PLAUNCF1F12NOS3NOS1
Benzamide SCHEMBL19877173 0.82 PLAU (0.68) PLAUNCF1F12NOS3NOS1
Methylglyoxal SCHEMBL6002250 0.82 F12 (0.68) PLAUNCF1F12NOS3NOS1
SCHEMBL3851423 0.81 F12 (0.66) PLAUNCF1F12NOS3NOS1
Hydrochloric Acid SCHEMBL27774395 0.81 F12 (0.66) PLAUNCF1F12NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119685827-B Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2026-05-12 CN claimed
US-12463229-B2 Bipolar ionomer membrane CAMX POWER LLC (US) 2025-11-04 US claimed
EP-3411430-B1 BIPOLAR IONOMER MEMBRANE CAMX POWER L L C (US) 2025-08-13 EP claimed
EP-4536356-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS Xenon Pharmaceuticals Inc. (CA) 2025-04-16 EP claimed
CN-119685827-A Environment-friendly composite corrosion and scale inhibitor and preparation method and application thereof 中国石油化工股份有限公司 2025-03-25 CN claimed
CN-118908892-A Amino isoquinoline derivative and application thereof in preparation of antiviral drugs 武汉大学 2024-11-08 CN claimed
CN-116478052-B Method for synthesizing 1-naphthylamine derivative by copper catalysis 江苏师范大学 2024-10-22 CN claimed
CN-108779275-B Bipolar ionomer membranes 坎麦克斯动力有限责任公司 2024-10-15 CN claimed
CN-112390755-B Heteroaryl method for amine 中国科学院理化技术研究所 2024-08-02 CN claimed
US-20240216900-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-07-04 US claimed
EP-0946520-A1 ISOQUINOLINAMINE AND PHTHALAZINAMINE DERIVATIVES WHICH INTERACT WITH CRF RECEPTORS NEUROGEN CORPORATION (US) 1999-10-06 EP claimed
EP-0943032-A1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME Consortium für elektrochemische Industrie GmbH (DE) 1999-09-22 EP claimed
WO-1999039575-A2 SYNERGISTIC BIOCIDAL ACTIVITY OF TERNARY COMPLEXES OF NEGATIVELY -CHARGED BIOCIDES (COMPONENT A), TRANSITION METAL IONS (COMPONENT B), AND NEUTRAL CHELATORS (COMPONENT C) YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1999-08-12 WO claimed
WO-1999011622-A1 AMINO-SUBSTITUTED COMPOUNDS, METHODS, AND COMPOSITIONS FOR INHIBITING PARP ACTIVITY GUILFORD PHARMACEUTICALS INC. (US) 1999-03-11 WO claimed
WO-1998051268-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL (FR) 1998-11-19 WO claimed
WO-1998027066-A1 ISOQUINOLINAMINE AND PHTHALAZINAMINE DERIVATIVES WHICH INTERACT WITH CRF RECEPTORS NEUROGEN CORPORATION (US) 1998-06-25 WO claimed
WO-1998026127-A1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES, AND PROCESS FOR USING THE SAME Consortium für elektrochemische Industrie GmbH (DE) 1998-06-18 WO claimed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP claimed
EP-0035244-B1 CYCLOALKA(4,5)PYRROLO(2,3-G)ISOQUINOLINES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND MEDICINES CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-05-08 EP claimed
EP-0010661-B1 ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-09-12 EP claimed