Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 2/20 | 0.35 |
| ▸ | RHOA | P61586 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931986 | 0.90 | THRA (0.42) | LMNAMRGPRX4THRATHRBALDH1A1 | |
| SCHEMBL4929174 | 0.89 | LMNA (0.40) | LMNAMRGPRX4THRATHRBALDH1A1 | |
| SCHEMBL5718494 | 0.88 | MEN1 (0.37) | MRGPRX4THRATHRBMEN1KMT2A | |
| SCHEMBL4932229 | 0.87 | PPARD (0.43) | MRGPRX4THRATHRBRHOCRHOA | |
| SCHEMBL4931458 | 0.87 | THRA (0.40) | THRATHRBALDH1A1MEN1KMT2A | |
| SCHEMBL5718202 | 0.86 | THRA (0.39) | LMNAMRGPRX4THRATHRBALDH1A1 | |
| SCHEMBL4930094 | 0.85 | THRA (0.48) | MRGPRX4THRATHRB | |
| SCHEMBL4928632 | 0.85 | THRA (0.43) | LMNATHRATHRBALDH1A1KDM4E | |
| SCHEMBL5119858 | 0.84 | LMNA (0.44) | LMNAMRGPRX4THRATHRBALDH1A1 | |
| SCHEMBL4931364 | 0.84 | LMNA (0.44) | LMNAMRGPRX4THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | LMNA 3893/4885MRGPRX4 119/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.