Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718202 | 0.95 | THRA (0.39) | LMNAALDH1A1THRBTHRANR2E1 | |
| SCHEMBL4931986 | 0.89 | THRA (0.42) | LMNAALDH1A1THRBTHRATACR1 | |
| SCHEMBL4922936 | 0.89 | LMNA (0.40) | LMNAALDH1A1THRBTHRATACR1 | |
| SCHEMBL4935507 | 0.87 | THRB (0.40) | LMNAALDH1A1THRBTHRA | |
| SCHEMBL5718204 | 0.87 | THRA (0.35) | ALDH1A1THRBTHRANR2E1CSF1R | |
| SCHEMBL4928755 | 0.85 | THRB (0.43) | LMNAALDH1A1THRBTHRAMRGPRX4 | |
| SCHEMBL4931227 | 0.85 | LMNA (0.45) | LMNAALDH1A1THRBTHRANR2E1 | |
| SCHEMBL5109577 | 0.85 | LMNA (0.45) | LMNAALDH1A1THRBTHRANR2E1 | |
| SCHEMBL5104500 | 0.85 | ALDH1A1 (0.52) | LMNAALDH1A1THRBTHRANR2E1 | |
| SCHEMBL4929575 | 0.85 | LMNA (0.40) | LMNAALDH1A1THRBTHRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | LMNA 3893/4885ALDH1A1 1818/4885THRB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.