Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 9/20 | 0.40 |
| ▸ | THRA | P10827 | 8/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718096 | 0.91 | MRGPRX4 (0.38) | PPARDMRGPRX4MMEACECPA1 | |
| SCHEMBL4926924 | 0.91 | PPARD (0.45) | PPARDMRGPRX4MMEACECPA1 | |
| SCHEMBL4927315 | 0.90 | THRA (0.48) | MRGPRX4MMEACECPA1ACE2 | |
| SCHEMBL4930757 | 0.90 | THRB (0.49) | PPARDMRGPRX4MMEACECPA1 | |
| SCHEMBL4934220 | 0.87 | MME (0.42) | PPARDMRGPRX4MMEACECPA1 | |
| SCHEMBL4929409 | 0.87 | ALDH1A1 (0.43) | MRGPRX4MMEACECPA1ACE2 | |
| SCHEMBL4931513 | 0.86 | THRB (0.41) | MRGPRX4THRBTHRA | |
| SCHEMBL4933436 | 0.85 | MRGPRX4 (0.40) | MRGPRX4MMEACECPA1ACE2 | |
| SCHEMBL4931818 | 0.85 | PPARD (0.46) | PPARDMRGPRX4MMEACECPA1 | |
| SCHEMBL4940742 | 0.85 | THRB (0.40) | MRGPRX4THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | PPARD 284/4885MRGPRX4 119/4885MME 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.