Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | F9 | P00740 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658905 | 0.79 | F9 (0.43) | ALDH1A1HPGDCYP1A2XBP1CYP2C19 | |
| SCHEMBL18269212 | 0.75 | MLKL (0.57) | ALDH1A1HPGDCYP1A2OPRM1OPRD1 | |
| SCHEMBL1479955 | 0.74 | ALDH1A1 (0.44) | ALDH1A1OPRM1OPRD1CTDSP1KMT2A | |
| SCHEMBL4148785 | 0.74 | MAPT (0.42) | ALDH1A1HPGDCYP1A2XBP1CYP2C19 | |
| SCHEMBL19863782 | 0.72 | CYP1A2 (0.39) | ALDH1A1HPGDCYP1A2OPRM1OPRD1 | |
| SCHEMBL586819 | 0.72 | GAA (0.46) | ALDH1A1HPGDCYP1A2KMT2AGAA | |
| SCHEMBL4826538 | 0.72 | GAA (0.46) | ALDH1A1HPGDCYP1A2KMT2AGAA | |
| SCHEMBL4163922 | 0.72 | AAK1 (0.54) | OPRM1OPRD1CTDSP1 | |
| SCHEMBL2302338 | 0.71 | PRKCZ (0.46) | CYP1A2CYP2C19KMT2AF9GAA | |
| SCHEMBL5103570 | 0.71 | HRH1 (0.44) | ALDH1A1HPGDCYP1A2KMT2AF9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | disclosed |
| US-20050272792-A1 | Benzimidazoles, process for their preparation and use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272792-A1 | Benzimidazoles, process for their preparation and use thereof as medicament | CYP2C19, CYP3A4, CYP2B6 | ALDH1A1 117/4885HPGD 3542/4885CYP1A2 15/4885 |
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | CYP2C19, CYP3A4, CYP2B6 | ALDH1A1 117/4885HPGD 3542/4885CYP1A2 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.