Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637787 | 0.90 | KIF11 (0.36) | PNMTKIF11RIPK1HDAC4HDAC2 | |
| SCHEMBL20963009 | 0.77 | KIF11 (0.46) | PNMTKIF11DAOHDAC4HDAC2 | |
| SCHEMBL4923756 | 0.75 | KIF11 (0.32) | KIF11RIPK1 | |
| SCHEMBL1599405 | 0.75 | TAAR1 (0.50) | RIPK1ALDH1A1 | |
| SCHEMBL9776758 | 0.73 | AOC3 (0.34) | — | |
| SCHEMBL45022 | 0.70 | ESR1 (0.44) | KIF11HDAC4HDAC2HDAC8ALDH1A1 | |
| SCHEMBL28391583 | 0.69 | HDAC4 (0.38) | PNMTKIF11RIPK1HDAC4HDAC2 | |
| SCHEMBL12110561 | 0.68 | PNMT (0.33) | PNMT | |
| SCHEMBL28107086 | 0.67 | HDAC4 (0.50) | KIF11RIPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL5485069 | 0.67 | HDAC4 (0.39) | KIF11HDAC4HDAC2HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125549-A1 | COUPLING OF LIVING CARBOCATIONIC POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-29 | — | — | US | disclosed |
| US-6469115-B1 | ROOM TEMPERATURE VULCANIZABLE POLYISOBUTYLENE POLYMER HAVING HYDROLYZABLE SILYL- FUNCTIONAL GROUPS POSITIONED AT OR NEAR MOLECULAR CHAIN ENDS | DOW CORNING CORPORATION | 2002-10-22 | — | — | US | disclosed |
| WO-2001087999-A2 | VIRTUALLY TELECHELIC SILYL-FUNCTIONAL POLYISOBUTYLENE | DOW CORNING CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |