Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194406 | 0.89 | SIRT2 (0.61) | MEN1KMT2AALDH1A1KCNK3KCNK9 | |
| SCHEMBL3356211 | 0.86 | MEN1 (1.00) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL31424193 | 0.86 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL259352 | 0.86 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL533767 | 0.84 | KCNK3 (0.81) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL16941525 | 0.83 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL10944964 | 0.82 | MEN1 (0.72) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL5742618 | 0.82 | RAB9A (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7181742 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL1991352 | 0.81 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | MCHR1, GPR119, MCHR2 | MEN1 1056/4885KMT2A 818/4885ALDH1A1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.