Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 5/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributylmethylammonium SCHEMBL4927209 | 1.00 | BBOX1 (0.44) | BBOX1CA1FABP3CES2CES1 | |
| Tributylmethylammonium SCHEMBL4925161 | 1.00 | BBOX1 (0.44) | BBOX1CA1FABP3CES2CES1 | |
| Tributylmethylammonium SCHEMBL4952826 | 0.98 | BBOX1 (0.45) | BBOX1CA1FABP3CES2CES1 | |
| Tributylmethylammonium SCHEMBL4917523 | 0.98 | BBOX1 (0.45) | BBOX1CA1FABP3CES2CES1 | |
| Tributylmethylammonium SCHEMBL4931562 | 0.98 | BBOX1 (0.45) | BBOX1CA1FABP3CES2CES1 | |
| Tributylmethylammonium SCHEMBL4921759 | 0.90 | BBOX1 (0.44) | BBOX1 | |
| Tributylmethylammonium SCHEMBL4951140 | 0.90 | BBOX1 (0.44) | BBOX1 | |
| Tributylmethylammonium SCHEMBL4926743 | 0.90 | BBOX1 (0.44) | BBOX1 | |
| Fumaric Acid SCHEMBL4929679 | 0.87 | BBOX1 (0.45) | BBOX1CA1FABP3CES2CES1 | |
| Fumaric Acid SCHEMBL4929346 | 0.87 | BBOX1 (0.45) | BBOX1CA1FABP3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312351-A1 | Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-12-18 | — | — | US | claimed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| US-20080312351-A1 | Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |