Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirisudanol SCHEMBL1650884 | 0.94 | HPGD (0.43) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| Pirisudanol SCHEMBL6376757 | 0.94 | HPGD (0.43) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| Pirisudanol SCHEMBL28086569 | 0.82 | APEX1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL5346682 | 0.81 | KDM4E (0.61) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL478873 | 0.80 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9232006 | 0.79 | KDM4E (0.51) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL29387458 | 0.79 | KDM4E (0.51) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL516267 | 0.79 | KDM4E (0.51) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL49262 | 0.76 | HPGD (0.45) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL27334611 | 0.75 | SGPL1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| CN-102275053-B | Welding robot system | GUANGZHOU AUTOMOBILE GROUP PASSENGER CARS CO LTD | 2014-12-03 | — | — | CN | claimed |
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | claimed |
| WO-2012116278-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | WO | claimed |
| CN-102275053-A | Welding robot system | — | 2011-12-14 | — | — | CN | claimed |
| WO-2011132171-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | WO | claimed |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | US | claimed |
| US-20100233112-A1 | SHAPE MEMORY POLYMER NETWORK USING HETEROCYCLIC GROUPS | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2010-09-16 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101484152-A | Therapeutic combination for painful medical conditions | SANOL ARZNEI SCHWARZ GMBH (DE) | 2009-07-15 | — | — | CN | claimed |
| WO-2007141018-A1 | THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS | SCHWARZ PHARMA AG (DE) | 2007-12-13 | — | — | WO | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| US-20070043120-A1 | Therapeutic combination for painful medical conditions | UCB PHARMA GMBH (DE) | 2007-02-22 | — | — | US | claimed |
| US-20070042969-A1 | Combination therapy for pain in painful diabetic neuropathy | SRZ PROPERTIES, INC. (US) | 2007-02-22 | — | — | US | claimed |
| EP-1725222-A2 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PSYCHIATRIC DISORDERS WITH COX-2 INHIBITORS ALONE AND IN COMBINATION WITH ANTIDEPRESSANT AGENTS | Pharmacia Corporation (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005084654-A2 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PSYCHIATRIC DISORDERS WITH COX-2 INHIBITORS ALONE AND IN COMBINATION WITH ANTIDEPRESSANT AGENTS | PHARMACIA CORPORATION (US) | 2005-09-15 | — | — | WO | claimed |
| US-5780055-A | BEAD PREPARED FROM MICROCRYSTALLINE CELLULOSE BY EXTRUSION-SPHERONIZATION AND FREEZE DRYING | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 1998-07-14 | — | — | US | claimed |
| WO-1998009597-A2 | CUSHIONING BEADS AND TABLET COMPRISING THE SAME CAPABLE OF FORMING A SUSPENSION | UNIVERSITY OF MARYLAND BALTIMORE (US) | 1998-03-12 | — | — | WO | claimed |
| EP-0116238-A1 | Therapeutic compositions and their use in enhancing brain function | BIOMEASURE, INC. (US) | 1984-08-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042969-A1 | Combination therapy for pain in painful diabetic neuropathy | GRIN2B, GRIN2A, GRIN3A | ALDH1A1 2350/4885HPGD 1595/4885KDM4E 1053/4885 |
| US-20100233112-A1 | SHAPE MEMORY POLYMER NETWORK USING HETEROCYCLIC GROUPS | H1-4, PNN, CD44 | ALDH1A1 4283/4885HPGD 56/4885KDM4E 2759/4885 |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | NOS2, NOS1, NOS3 | ALDH1A1 204/4885HPGD 9/4885KDM4E 2388/4885 |
| US-20070043120-A1 | Therapeutic combination for painful medical conditions | PDE1B, CA2, CACNA1S | ALDH1A1 2182/4885HPGD 790/4885KDM4E 3341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.