SCHEMBL4926475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4930242	0.97	POLB (0.49)	L3MBTL1POLBRECQLLMNACYP1A2
	SCHEMBL5402996	0.95	POLB (0.54)	L3MBTL1POLBRECQLCYP1A2CYP3A4
	SCHEMBL5403428	0.92	APP (0.49)	LMNAALDH1A1HTTKDM4EMAPK1
	SCHEMBL5403132	0.89	LMNA (0.48)	LMNAALDH1A1HTTKDM4EMAPK1
	SCHEMBL4931284	0.88	PPARA (0.46)	LMNAALDH1A1KDM4EAPPMAPT
	SCHEMBL4921807	0.88	LMNA (0.46)	POLBLMNAKMT2AAPPMAPT
	SCHEMBL5401148	0.88	LMNA (0.46)	LMNAALDH1A1KDM4EAPPMAPT
	SCHEMBL5392202	0.88	RAB9A (0.55)	L3MBTL1POLBLMNAALDH1A1USP2
	SCHEMBL5398713	0.88	KMT2A (0.50)	L3MBTL1POLBLMNACYP1A2CYP2C19
	SCHEMBL5395620	0.88	KMT2A (0.50)	LMNACYP1A2CYP3A4TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.