Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336862 | 0.90 | POLB (0.49) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL23512823 | 0.90 | POLB (0.49) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL1336860 | 0.90 | POLB (0.49) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL18970299 | 0.90 | POLB (0.49) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL8321789 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL26253773 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAMAPK1POLB | |
| SCHEMBL21225112 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAMAPK1HDAC3 | |
| SCHEMBL21225111 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAMAPK1HDAC3 | |
| SCHEMBL27414989 | 0.80 | POLB (0.51) | ALDH1A1MAPTGAAMAPK1HDAC3 | |
| SCHEMBL22873959 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAMAPK1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108706-A1 | Chemical resection of pancreas | BERGERON RAYMOND J JR | 2008-05-08 | — | — | US | disclosed |
| US-5962533-A | ANTITUMOR AGENTS; ANTIDIARRHEA AGENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108706-A1 | Chemical resection of pancreas | RNASE1, AMY2A, IAPP | ALDH1A1 457/4885MAPT 4839/4885GAA 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.