SCHEMBL4928264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4929843	0.88	HDAC3 (0.56)	MMP12HDAC3HDAC4HDAC1HDAC7
	SCHEMBL6450445	0.81	MMP12 (1.00)	MMP12CD274GLAGAAMMP2
	SCHEMBL277558	0.79	MEN1 (0.64)	MMP12KMT2AMEN1L3MBTL1CD274
	SCHEMBL279580	0.78	KMT2A (0.62)	MMP12KMT2AMEN1L3MBTL1CD274
	SCHEMBL5000477	0.78	AKT3 (0.66)	MMP12KMT2AMEN1L3MBTL1LMNA
	SCHEMBL23983071	0.77	NPC1 (0.57)	MMP12KMT2ACD274GAAMMP2
	SCHEMBL277405	0.77	KMT2A (0.61)	MMP12KMT2AMEN1L3MBTL1CD274
	SCHEMBL11919030	0.77	KMT2A (0.61)	MMP12KMT2AMEN1L3MBTL1CD274
	Hydrochloric Acid SCHEMBL21625705	0.77	NPC1 (0.56)	MMP12KMT2ACD274GAAMMP2
	SCHEMBL13354501	0.76	KMT2A (0.60)	MMP12KMT2AMEN1L3MBTL1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.