Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846604 | 0.82 | APP (0.61) | APPESR2ESR1HSD17B1HSD17B2 | |
| SCHEMBL18386374 | 0.73 | CNR2 (0.30) | — | |
| SCHEMBL1917704 | 0.72 | TAAR1 (0.56) | ESR2ESR1TAAR1HIF1AHTR3A | |
| SCHEMBL11887463 | 0.70 | HSD17B1 (0.38) | APPESR2ESR1HSD17B1HSD17B2 | |
| SCHEMBL2671959 | 0.69 | CYP2D6 (0.50) | APPKDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL22238939 | 0.69 | RAB9A (0.51) | APPKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18418550 | 0.69 | BDKRB2 (0.38) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18418544 | 0.69 | APP (0.37) | APPESR1HIF1ATSHRKDM4E | |
| SCHEMBL22241057 | 0.69 | PTPRF (0.36) | APPESR2ESR1TSHRNFKB1 | |
| SCHEMBL18418547 | 0.68 | APP (0.31) | APPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120105783-A1 | PATTERNED ELECTRONIC AND POLARIZATION OPTICAL DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2012-05-03 | — | — | US | disclosed |